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Tyrosine Kinase Inhibitor

Quality-of-Life Assessment for Carcinoid Tumor

Phase 2

Waitlist Available

Led By Renuka Iyer

Research Sponsored by Roswell Park Cancer Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 3 years (telephone contact is acceptable).

Awards & highlights

Study Summary

This trial tests whether nintedanib can treat neuroendocrine tumors by stopping the growth of new blood vessels necessary for tumor growth.

Eligible Conditions

Carcinoid Tumor
Neuroendocrine Tumors

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 3 years (telephone contact is acceptable).

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 3 years (telephone contact is acceptable).

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 years (telephone contact is acceptable). for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

PFS

Secondary outcome measures

Change in Quality of Life Score

Clinical Response (Complete Response + Partial Response) Measured Using Standard RECISTv1.1 Criteria

Median OS

+2 more

Other outcome measures

Biomarker Levels

Change in Cytokine Expression

Change in Growth Factors

+2 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Treatment (nintedanib)Experimental Treatment4 Interventions

Patients receive nintedanib PO BID on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Nintedanib

2015

Completed Phase 4

~3680

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Comprehensive Cancer NetworkNETWORK

115 Previous Clinical Trials

7,603 Total Patients Enrolled

1 Trials studying Carcinoid Tumor

30 Patients Enrolled for Carcinoid Tumor

Roswell Park Cancer InstituteLead Sponsor

402 Previous Clinical Trials

30,826 Total Patients Enrolled

1 Trials studying Carcinoid Tumor

14 Patients Enrolled for Carcinoid Tumor

Renuka IyerPrincipal InvestigatorRoswell Park Cancer Institute

7 Previous Clinical Trials

175 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Have there been previous attempts to examine the efficacy of this medication?

"Currently, 8 Phase 3 clinical trials studying Pharmacological Study are active with 67 total studies. Most of these activities take place in Orlando, Florida; however, there are 7132 medical centres working on this research globally."

Answered by AI

Are there vacancies within this trial for participants?

"According to clinicaltrials.gov, the trial that was first publicised on May 15th 2015 is no longer recruiting participants. The most recent edit occurred on November 8th 2022. Despite this, there are still a plethora of other trials actively searching for patients at present."

Answered by AI

What is the customary application for Pharmacological Study?

"Adenocarcinoma is often treated with Pharmacological Study, though it may be useful in other cases requiring amino acid supplementation therapy, managing renal dysfunction or addressing kidney failure."

Answered by AI

To what extent could patients be at risk from participating in a Pharmacological Study?

"Taking into account the Phase 2 status of this pharmacological study, we rate its safety at a score of 2. This is based on limited data concerning efficacy and multiple rounds affirming safety."

Answered by AI

What is the scope of enrollment for this trial?

"This research is not open to new enrolment at this time. Initially available on May 15th 2015, its latest update was November 8th 2022. If you are searching for other trials, 2500 clinical studies involving argentaffinoma and 67 examinations related to pharmacology are currently recruiting patients."

Answered by AI

Is this research pioneering in its approach?

"Since 2007, Pharmacological Study has been an area of research interest. Baxter Healthcare Corporation launched the first clinical trial in that year for 4640 participants and was granted Phase 4 drug approval following its completion. Currently, 67 active trials are underway throughout 33 countries over 1103 cities."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

2015. "Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02399215.