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Radiation Therapy

Stratum 1 for Brain Tumor

Phase 2

Waitlist Available

Led By Thomas E. Merchant, D.O., Ph.D.

Research Sponsored by St. Jude Children's Research Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months after the enrollment of the last therapeutic patient

Awards & highlights

Study Summary

This trial was conducted to compare two types of radiation therapy in order to determine which one is more effective in treating cancer while also causing less damage to surrounding healthy tissue.

Eligible Conditions

Brain Tumor

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months after the enrollment of the last therapeutic patient

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months after the enrollment of the last therapeutic patient

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months after the enrollment of the last therapeutic patient for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Local Tumor Control

Trial Design

2Treatment groups

Experimental Treatment

Group I: Stratum 2Experimental Treatment1 Intervention

High-grade glioma

Group II: Stratum 1Experimental Treatment1 Intervention

Ependymoma, craniopharyngioma, low-grade glioma

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Radiation Therapy

2017

Completed Phase 3

~7250

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

St. Jude Children's Research HospitalLead Sponsor

428 Previous Clinical Trials

5,306,252 Total Patients Enrolled

Thomas E. Merchant, D.O., Ph.D.Principal InvestigatorSt. Jude Children's Research Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research protocol inclusive of geriatric participants?

"Patients who hope to take part in this trial must be between 8 Months and 25 years old. Separately, there are 376 studies available for minors (under 18) as well as 2,521 trials open to seniors over 65."

Answered by AI

Is it possible for me to become a participant in this trial?

"Prerequisites for being accepted into this clinical trial are a diagnosis of nervous system neoplasms and an age between 8 Months and 25. Around 202 participants will be selected."

Answered by AI

Are there still openings for volunteers in this research?

"Data hosted on clinicaltrials.gov suggests that, while this medical study had originally posted recruitment materials in June 1997 and was updated as recently as April 2022, it is not currently searching for patients to enrol. Nevertheless, there are still 2762 other studies actively recruiting participants at the moment."

Answered by AI

To what extent could this treatment be detrimental to human health?

"Despite there being some research backing its safety, the lack of data on efficacy merits a rating of 2 out of 3. This is in accordance with it being a Phase 2 trial."

Answered by AI

Recent research and studies

International Journal of Radiation Oncology*Biology*PhysicsJournal

Longitudinal Investigation of Adaptive Functioning Following Conformal Irradiation for Pediatric Craniopharyngioma and Low-grade Glioma

Netson, Kelli L., Heather M. Conklin, Shengjie Wu, Xiaoping Xiong, and Thomas E. Merchant. 2013. “Longitudinal Investigation of Adaptive Functioning Following Conformal Irradiation for Pediatric Craniopharyngioma and Low-grade Glioma”. International Journal of Radiation Oncology*biology*physics. Elsevier BV. doi:10.1016/j.ijrobp.2012.10.031.

clinicaltrials.govStudy

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

1997. "A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00187226.