This trial is evaluating whether 68Ga-FAPI will improve 1 primary outcome in patients with Malignancies. Measurement will happen over the course of 24 months.
This trial requires 30 total participants across 1 different treatment group
This trial involves a single treatment. 68Ga-FAPI is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
"Although the majority of patients diagnosed with cancer will not survive, some can do well with the best medical treatment available. However, many will eventually fall into remission from the initial cancer, but will then not suffer cancer again. Although cancer cannot definitely be cured, patients can find effective treatment and live a relatively long time." - Anonymous Online Contributor
"Most cancer is caused by environmental, viral and genetic factors, but not all cancers are caused by environmental factors. Environmental and lifestyle factors are the leading causes of cancer, causing 80% of all cancers worldwide. Tobacco smoking alone accounts for about 30% of cancer deaths worldwide. Vaccinations against certain infectious, viral, genetic and environmental agents may prevent some cancers." - Anonymous Online Contributor
"1.1 million people die from cancer a year in the United States. 1.1 million new cancers are diagnosed a year in the United States. More than 6.1 million new cancers are diagnosed in people over 50 years old a year in the United States. More than 6100 people are diagnosed with cancer at the time of death a year in the United States. More than 1.0 million Americans have an incurable cancer. 2.0 million Americans know that they have incurable cancer. 3.7% of cancer cases can be prevented. 3.5% of cancer cases can be prevented." - Anonymous Online Contributor
"Cancer treatment options can be divided into surgical, medical, and complementary treatments. Cancer surgery is usually the first line of treatment. Often, cancer treatment is also in conjunction with cancer chemotherapy. Radiation therapy can occur in conjunction with chemotherapy or surgery. Supportive care may accompany medical cancer treatment. Supportive care can take the form of symptom management, which may include pain management or emotional support, or supportive care that offers socialization, in a compassionate and warm environment." - Anonymous Online Contributor
"Cancer is an uncontrolled abnormal buildup of cells in tissues that no longer work as they should. It is sometimes called the body's war on itself." - Anonymous Online Contributor
"Some signs involve the skin or mucous membranes, including redness or tenderness. Symptoms of cancer may include the sensation of a mass in the abdominal cavity, a lump in the breast or rectum or pain in one or both legs or feet. Other signs may include unexplained weight loss, unexplained tiredness, bleeding, swelling, bone tenderness or pain, nausea, vomiting, unexplained itchiness, unexplained painless discharge from the bladder, bleeding from the nose or mouth, unexplained hair loss, unexplained muscle or joint pain, unexplained loss of appetite or unexplained blood loss from the anus or nose." - Anonymous Online Contributor
"Results from a recent paper of the present study do not support the proposition that improved quality of life, as measured by QOL, is seen with the use of 68Ga-fapi for patients with advanced cancer." - Anonymous Online Contributor
"We had a lot of problems with 68Ga-FAP in our practice. We have reported on the most frequent side effects in this study. Symptoms were mostly mild (such as nausea, vomiting, and headache) and could have been caused by more serious serious side-effects (such as liver damage. However, for some patients these problems were probably not serious at all. The most common side effect is fatigue which usually only affects women and can happen at the same time as breast pain." - Anonymous Online Contributor
"These studies did not demonstrate any significant increase in the use of 68Ga-fapi for oncology indications, as compared with a baseline period of 3 years. This indicates that clinical practice and not the use of a radiopharmaceutical for therapeutic or diagnostic imaging is responsible for this pattern of use. If the trend persists, these data may impact the uptake for therapeutic use of this radionuclide. These studies cannot refute the hypothesis of the likelihood of finding a meaningful benefit in clinical practice, and, as a consequence, it may be prudent to continue to use 68Ga-fapi for imaging oncology in the future." - Anonymous Online Contributor
"Even though there still exist many unanswered questions, advances have proven that cancer occurs as a multidisciplinary disease. The latest research on cancer in the year 2014 is very informative and can provide a better look on future developments on how to prevent, detect and treat cancers. A big improvement was made in the field of treatment of cancer. Still though the treatment modalities like chemotherapy, radiation and biological therapy as well as antibody-based therapies have improved in terms of improved treatment results, the problem of relapse after treatment exists in cancer. A new generation of drugs with anti-cancer properties are also being made available in the form of monoclonal antibodies (Mabs)." - Anonymous Online Contributor
"It is hard to define life expectancy. But if one were to give a 100 year survival rate, their life wouldn’t make a difference. What you do make a huge difference.\nIt’s hard to define life expectancy. But if one were to give a 100 year survival rate, their life wouldn’t make a difference. What you do make a huge difference.\nIt's also hard to define the life expectancy, because a person’s disease can still be with you, or it can be over, with no warning." - Anonymous Online Contributor
"We summarize the current scientific knowledge on cancer development, and propose a classification of primary cancer (Figure 1), with a brief description for each primary cancer. There are some misconceptions and mistakes in the classification; for example, melanoma is a cancer of melanocytes. The cause of a given primary cancer is probably the result of a complex interplay of many factors: genetics, the environment, lifestyle, etc.\nWhy do people develop [type 2 diabetes](https://www.withpower.com/clinical-trials/type-2-diabetes) mellitus, and what happens if they don't get it treated? Diabetes was a prevalent disease prior to the 20th century due to the fact that people with diabetes tended to get a higher body fat percentage." - Anonymous Online Contributor