This trial is testing whether a certain type of cancer treatment is more effective when given to patients who also test positive for a specific biomarker. Blood will be taken from patients to test for the biomarker, and those who test positive will be randomly assigned to receive either one type of treatment or a combination of two treatments. The goal is to see if the combination treatment is more effective at reducing the biomarker in patients' blood.
- Melanoma Stage II
1 Primary · 8 Secondary · Reporting Duration: Through completion of follow-up (estimated to be 48 months)
Side Effects for
2 Treatment Groups
Arm 2: Atezolizumab
1 of 2
Arm 1: Atezolizumab + Tiragolumab
1 of 2
244 Total Participants · 2 Treatment Groups
Primary Treatment: ctDNA · No Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · All Participants · 4 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Is this a novel clinical trial?
"ctDNA has had a long history, with the first study being completed over a decade ago in 2008. The drug went through Phase 2 approval after the initial study and there are now 357 active trials taking place all over the world." - Anonymous Online Contributor
Could you please list other research projects that have utilized ctDNA?
"In 2008, ctDNA was first studied at Illinois Cancer Care. As of now, there have been a total of 79 completed clinical trials with 357 more currently underway. A large number of these studies are based in Duarte, Missouri." - Anonymous Online Contributor
How many people fit the requirements for this research?
"Yes, this is an active trial recruiting patients. The listing on clinicaltrials.gov reveals that the study was posted on November 8th, 2020 and last updated two days later. They are looking for 244 people to participate at 6 sites." - Anonymous Online Contributor
Does this research project have a broad reach in terms of the number of hospitals participating?
"At the moment, there are 6 sites where this trial is taking place. They are in Duarte, Saint Louis and New Haven as well as three other locations. If you want to take part in this trial, it would be best to choose a location near you so that travelling isn't too much of an inconvenience." - Anonymous Online Contributor
What is the official stance of the FDA on ctDNA?
"Currently, there is not enough data to confirm ctDNA's efficacy. However, because there are Phase 2 clinical trial results supporting its safety, our team has given it a rating of 2." - Anonymous Online Contributor
Are there any available positions for patients in this trial?
"The information available on clinicaltrials.gov supports that this trial is looking for volunteers at this time. This specific trial was first posted on November 8th, 2020 and updated two days ago. In total, 244 people are needed for the study taking place at 6 different locations." - Anonymous Online Contributor