Study Summary
This trial is looking at the acute effects of cannabis constituents on HIV-NP, long-term effects of cannabis use, and the impact of cannabis on endocannabinoid function in people living with HIV-NP.
- HIV-associated Neuropathy
- Complex Regional Pain Syndrome
- Cannabis
Treatment Effectiveness
Effectiveness Progress
Study Objectives
2 Primary · 6 Secondary · Reporting Duration: participants will be queried on a daily basis for six months using text messaging
Trial Safety
Safety Progress
Trial Design
3 Treatment Groups
Medium CBD session
1 of 3
High CBD session
1 of 3
Low CBD session
1 of 3
Active Control
120 Total Participants · 3 Treatment Groups
Primary Treatment: Medium CBD session · No Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 7 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Could you explain what the risks are for a person taking CBD?
"While there is some data supporting the safety of Medium CBD, as this is only a Phase 2 trial, none of it supports efficacy. Therefore, it received a score of 2." - Anonymous Online Contributor
Have there been similar trials like this one in the past?
"Currently, there are 35 on-going trials for Medium CBD session in 5 different countries. The first trial was conducted 6 years ago in 2015 and completed both its Phase 2 & 3 drug approval stages. Since then, 61 more trials have been successfully finished." - Anonymous Online Contributor
Are there presently any available slots for this clinical trial?
"The trial you are referring to is still recruiting patients, as indicated by the listing on clinicaltrials.gov. This study was first posted on July 1st, 2018 and has since been updated on January 10th, 2022." - Anonymous Online Contributor
How many people are joining this clinical trial?
"That is correct. The listing on clinicaltrials.gov does show that the research team is currently looking for study subjects. This particular trial was first made public on July 1st, 2018 and received its most recent update on January 10th, 2022. A total of 120 individuals will be enrolled at a single location." - Anonymous Online Contributor
Can you please compare and contrast this clinical trial with others involving Medium CBD session?
"There are currently 35 ongoing studies investigating the effects of Medium CBD session. Out of these, 3 are in Phase 3. Most trials originate from Hartford, Connecticut but there are 51 different locations running these sorts of tests." - Anonymous Online Contributor
What are the primary goals of this research project?
"The primary outcome of this six-month long clinical trial will be daily pain intensity levels as reported by participants, evaluated using an 11-point numerical scale. Secondary objectives includePhase 1 - the Neuropsychological Assessment Battery, Phase 1 - the von Frey test, and Phase 1 - the Marijuana subscale (M-scale) of the Addiction Research Center Inventory (ARCI)." - Anonymous Online Contributor