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brexucabtagene autoleucel for Mantle Cell Lymphoma (ZUMA-2 Trial)
ZUMA-2 Trial Summary
This trial is testing a new treatment for mantle cell lymphoma, a type of cancer.
- Mantle Cell Lymphoma (MCL)
ZUMA-2 Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.ZUMA-2 Trial Design
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Who is running the clinical trial?
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- You have a history of seizures, stroke, memory loss, or any conditions that affect your brain or nervous system.
- Group 1: Axicabtagene ciloleucel/brexucabtagene autoleucel (KTE-X19)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the cumulative enrollment figure for this clinical trial?
"At this juncture, no further enrolment is being accepted for the trial. It was first posted on November 9th 2015 and last edited May 4th 2022. Nevertheless, there are 1,720 other trials actively recruiting people with lymphoma and 894 studies seeking participants for brexucabtagene autoleucel treatments."
Are there any other scholarly accounts of the efficacy of brexucabtagene autoleucel?
"In 1997, the City of Hope Comprehensive Cancer Center began researching brexucabtagene autoleucel. To this day, 1275 clinical trials have been completed and 894 studies are currently active; many of them residing in Nashville, Tennessee."
Are there any vacancies available for participants in this experiment?
"According to the information posted on clinicaltrials.gov, this particular medical trial is no longer actively searching for participants as it was last edited on May 4th 2022. While this study has been concluded, there are 2614 other trials still open and recruiting patients."
In what conditions has brexucabtagene autoleucel exhibited the most efficacy?
"Brexucabtagene autoleucel is a proven therapeutic for treating lung cancers, but it also has application in multiple sclerosis and leukemia (including myelocytic acute refractory b-cell precursor acute lymphoblastic leukemia)."
Has the Food and Drug Administration granted permission for brexucabtagene autoleucel to go into circulation?
"Taking into consideration the fact that brexucabtagene autoleucel is in Phase 2 trials and lacks efficacy data, its safety rating was set at a modest 2."
How many healthcare facilities are currently administering this clinical trial?
"The current trial encompasses 24 sites, including locations in Nashville, Tampa and Columbus. To reduce the amount of travel necessary if you join the study, it is wise to select a site nearest to your residence."
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