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Rituximab + Chemotherapy for Mantle Cell Lymphoma
Study Summary
This trial is testing if a combination of drugs, including Rituximab, will be more effective than current treatments for Mantle Cell Lymphoma.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2016 Phase 2 & 3 trial • 86 Patients • NCT03002038Trial Design
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- My heart's pumping ability is significantly reduced.I have hepatitis or hepatitis B virus infection.I have mantle cell lymphoma and have not received any treatment for it.I have had treatments like chemotherapy for my mantle cell lymphoma.I have no other active cancers except possibly skin or cervical cancer.I am older than 18 years.My liver and kidney functions are within the required ranges.My cancer is at any stage.I can take care of myself and am up and about more than half of my waking hours.My cancer has spread to my brain or spinal cord.I have a tumor larger than 1.5 cm.
- Group 1: R-MACLO/IVAM
- Approved for 20 Other Conditions - This treatment demonstrated efficacy for 20 other conditions.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What are some of the primary conditions that Rituximab is used to treat?
"Rituximab can be used to fight three types of cancer: lung cancers, small cell lung cancer (sclc), and polyangium."
Can you give some examples of other times Rituximab has been used in medical research?
"Presently, 442 Rituximab trials are in Phase 3 and 1952 studies are ongoing. Most of these research projects are situated in Bethesda, Maryland; however, there are a total of 68731 clinical trial sites for this medication."
Are we currently recruiting participants for this research?
"No, this particular study is not looking for new participants. However, there are over 3000 other clinical trials that might be a match for patients seeking to enroll in medical research."
How many people will be given the opportunity to participate in this test program?
"This study is not recruiting at the moment. It was originally posted on 3/25/2009 and updated for the last time on 8/17/2022. However, there are currently 1762 clinical trials actively enrolling patients with mantle cell lymphoma (mcl) and 1952 trials for Rituximab admitting patients right now."
Can you quantify the risks associated with Rituximab?
"Rituximab's safety is unproven but there is some data supporting its use, so it received a score of 2."
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