← Back to Search

Other

Liquid Manuka Honey for Esophagitis

Phase 2
Waitlist Available
Led By Lawrence B. Berk, MD, PhD
Research Sponsored by Radiation Therapy Oncology Group
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 4 and 12 weeks from the start of treatment
Awards & highlights

Study Summary

RATIONALE: Manuka honey may prevent or reduce esophagitis-related pain caused by chemotherapy and radiation therapy. It is not yet known whether Manuka honey is more effective than standard care in preventing pain. PURPOSE: This randomized phase II clinical trial is studying Manuka honey to see how well it works in preventing esophagitis-related pain in patients receiving chemotherapy and radiation therapy for lung cancer.

Eligible Conditions
  • Esophagitis
  • Lung Cancer
  • Pain
  • Swallowing Difficulty

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 4 and 12 weeks from the start of treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 4 and 12 weeks from the start of treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Radiation Esophagitis-related Pain at 4 Weeks as Measured by the Numerical Rating Pain Scale for Pain on Swallowing (NRPS)
Secondary outcome measures
Adverse Events Associated With Manuka Honey Using CTCAE v4.0
Dysphagia Via Daily Patient Log
Nutritional Status (Change in Serum Prealbumin Levels From Baseline to 4 Weeks)
+6 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Lozenge Manuka HoneyExperimental Treatment1 Intervention
Manuka honey in lozenge form
Group II: Liquid Manuka HoneyExperimental Treatment1 Intervention
Manuka honey in liquid form
Group III: Supportive CareActive Control1 Intervention
Standard supportive care
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Honey
FDA approved
Honey
FDA approved

Find a Location

Who is running the clinical trial?

Radiation Therapy Oncology GroupLead Sponsor
190 Previous Clinical Trials
64,764 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,708 Previous Clinical Trials
40,932,566 Total Patients Enrolled
4 Trials studying Esophagitis
336 Patients Enrolled for Esophagitis
NRG OncologyOTHER
232 Previous Clinical Trials
100,616 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer
2012. "Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01262560.
~12 spots leftby May 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top