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1 for Lung Disease

Phase 3
Waitlist Available
Led By Patrick McNamara, MD
Research Sponsored by The Hospital for Sick Children
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 hours after drug administration and 24 hours post recruitment
Awards & highlights

Study Summary

The purpose of this study is to investigate the effects of intravenous furosemide on cardio-respiratory performance in neonates receiving a packed red blood cell (PRBC) transfusion who are considered at high risk of volume overload.

Eligible Conditions
  • Lung Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 hours after drug administration and 24 hours post recruitment
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 hours after drug administration and 24 hours post recruitment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cardiac chamber volume loading.
Secondary outcome measures
Changes in electrolyte balance, body weight and urine output.
Clinical cardio-respiratory stability (heart rate, blood pressure, respiratory rate, oxygen saturation, and oxygen requirement).
Myocardial performance, cardiac input and output and pulmonary hemodynamics (echocardiograph exam).

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: 1Experimental Treatment1 Intervention
Furosemide
Group II: 2Placebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Furosemide
FDA approved

Find a Location

Who is running the clinical trial?

The Hospital for Sick ChildrenLead Sponsor
689 Previous Clinical Trials
6,945,357 Total Patients Enrolled
Patrick McNamara, MDPrincipal InvestigatorThe Hospital for Sick Children, Toronto Canada
1 Previous Clinical Trials
20 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Using Furosemide to Prevent Fluid Overload During Red Blood Cell Transfusion in Neonates
2007. "Using Furosemide to Prevent Fluid Overload During Red Blood Cell Transfusion in Neonates". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00618852.
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