This trial is testing whether a drug called D-cycloserine can help people with chronic lower back pain.
- Lower Back Pain
2 Primary · 14 Secondary · Reporting Duration: 12 week
Side Effects for
Awards & Highlights
2 Treatment Groups
1 of 2
1 of 2
244 Total Participants · 2 Treatment Groups
Primary Treatment: D-cycloserine · Has Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · All Participants · 8 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
- Pinto, Camila Bonin, Jannis Bielefeld, Joana Barroso, Byron Yip, Lejian Huang, Thomas Schnitzer, and A. Vania Apkarian. 2022. “Chronic Pain Domains and Their Relationship to Personality, Abilities, and Brain Networks”. Pain. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/j.pain.0000000000002657.
- Pinto CB, Bielefeld J, Barroso J, Yip B, Huang L, Schnitzer T, Apkarian AV. Chronic pain domains and their relationship to personality, abilities, and brain networks. Pain. 2022 Apr 20:10.1097/j.pain.0000000000002657. doi: 10.1097/j.pain.0000000000002657. Online ahead of print. No abstract available.
- Pinto CB, Bielefeld J, Barroso J, Yip B, Huang L, Schnitzer T, Apkarian AV. Chronic pain domains and their relationship to personality, abilities, and brain networks. Pain. 2023 Jan 1;164(1):59-71. doi: 10.1097/j.pain.0000000000002657. Epub 2022 Apr 20. No abstract available.
- Thomas J. Schnitzer 2018. "D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03535688.
Frequently Asked Questions
How many people fit the criteria to participate in this clinical trial?
"That is correct. The listing on clinicaltrials.gov does show that the trial administrators are still looking for patients to enroll. This particular trial was posted on March 30th, 2018 and updated January 6th, 2022. They are hoping to have 244 people participate at one location." - Anonymous Online Contributor
Will D-cycloserine have any negative consequences for test subjects?
"D-cycloserine has received a safety score of 2. This is because, although there is evidence that it is safe, there have been no clinical trials demonstrating its efficacy." - Anonymous Online Contributor
How does D-cycloserine usually help patients?
"D-cycloserine is often used to treat patients that have failed to respond to conventional therapies. It can also be an effective way of treating other conditions such as tuberculosis, extrapulmonary tuberculosis, and pulmonary tuberculosis." - Anonymous Online Contributor
What other scientific papers feature D-cycloserine?
"Currently, there are 9 D-cycloserine studies underway. 2 of those trials have progressed to Phase 3 clinical testing. The great majority of these tests are taking place in Baltimore, MD; however, 23 sites across the country are running similar investigations." - Anonymous Online Contributor
Are there any available vacancies for people who want to participate in this experiment?
"That is correct, the clinicaltrials.gov website has information indicating that this study is still looking for participants. The trial was originally posted on March 30th, 2018 and updated January 6th, 2022. They are currently seeking 244 patients from 1 site." - Anonymous Online Contributor