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Intervention for Kidney Failure

Phase 2
Waitlist Available
Led By Pia Kontos, PhD
Research Sponsored by Toronto Rehabilitation Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 0, 8, 16, 28 weeks
Awards & highlights

Study Summary

Exercise training for older hemodialysis patients can greatly improve many of the negative effects and poor health outcomes associated with end-stage kidney disease. Exercise has yet to be incorporated effectively and systematically into routine care. Exercise programs remain rare. When such programs are implemented, their participation rates vary, and they neglect home and community-based activities, as well as the involvement of family caregivers to support and reinforce exercise. This study is intended to address these limitations by introducing a highly accessible and compelling educational film, Fit for Dialysis, designed to introduce, motivate, and sustain exercise for wellness amongst older hemodialysis patients, and exercise counseling and support by family caregivers, nephrologists, and nurses. The objective of this clinical trial is to determine whether and in what ways Fit for Dialysis improves outcomes and influences knowledge/attitudes regarding the importance of exercise-based principles of wellness in the context of end-stage renal disease. Ultimately Fit for Dialysis could be used as a model for dialysis education that supports guideline recommendations that exercise be incorporated into the care and treatment of dialysis patients.

Eligible Conditions
  • Kidney Failure

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0, 8, 16, 28 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 0, 8, 16, 28 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Adherence measured by the percentage of time participants achieved at least 70% of prescribed targets of minutes and intensity of exercise per week.
Change in functional exercise capacity measured by the 2-Minute Walk Test
Secondary outcome measures
Change in basic mobility using the Timed Up and Go
Change in number of steps using a pedometer
Change in self-assessment of functional of capacities and peak metabolic equivalents using the Duke Activity Status Index
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment1 Intervention
A research-based film (Fit for Dialysis) and a 16-week exercise program involving activities during dialysis, at home, and in the community.
Group II: ControlActive Control1 Intervention
The 16-week exercise program involving activities during dialysis, at home, and in the community.

Find a Location

Who is running the clinical trial?

Toronto Rehabilitation InstituteLead Sponsor
50 Previous Clinical Trials
5,561 Total Patients Enrolled
Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,345 Previous Clinical Trials
26,453,454 Total Patients Enrolled
4 Trials studying Kidney Failure
5,488 Patients Enrolled for Kidney Failure
Pia Kontos, PhDPrincipal InvestigatorUniversity Health Network, Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~5 spots leftby May 2025