Triferic for Kidney Failure

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Children's Mercy Hospital, Kansas City, MOKidney FailureTriferic - Drug
Eligibility
6 - 17
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether it is safe to give Triferic iron to children with chronic kidney disease who are on dialysis.

Eligible Conditions
  • Kidney Failure

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: 44 weeks

44 weeks
Assess the ability of Triferic to maintain hemoglobin in pediatric CKD-5HD patients
Assess the change in reticulocyte hemoglobin content (CHr).
Assess the incidence of adverse events of Triferic administration via dialysate and IV in pediatric CKD-5HD patients
Assess the proportion of patients maintaining hemoglobin between 10.5-12.0 g/dL compared to baseline

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Historic Control Observational Arm
1 of 2
Triferic via IV and Hemodialysate
1 of 2

Active Control

Experimental Treatment

150 Total Participants · 2 Treatment Groups

Primary Treatment: Triferic · No Placebo Group · Phase 3

Triferic via IV and Hemodialysate
Drug
Experimental Group · 1 Intervention: Triferic · Intervention Types: Drug
Historic Control Observational ArmNoIntervention Group · 1 Intervention: Historic Control Observational Arm · Intervention Types:
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ferric pyrophosphate citrate
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 44 weeks

Who is running the clinical trial?

Rockwell Medical Technologies, Inc.Lead Sponsor
19 Previous Clinical Trials
1,868 Total Patients Enrolled
1 Trials studying Kidney Failure
12 Patients Enrolled for Kidney Failure
Raymond D Pratt, MD FACPStudy DirectorRockwell Medical, Inc
3 Previous Clinical Trials
82 Total Patients Enrolled

Eligibility Criteria

Age 6 - 17 · All Participants · 10 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Frequently Asked Questions

Could I join this clinical trial?

"Up to 150 paediatric patients with chronic kidney disease, who have been receiving hemodialysis treatment for at least 3 months, and weigh more than 11lbs (5kg) are eligible for this study. Additional requirements include that the patient has a suitable vascular access for hemodialysis treatment and is between 6 months and 17 years old." - Anonymous Online Contributor

Unverified Answer

Are there any available positions for people who want to participate in this clinical trial?

"Yes, this trial is looking for participants and has been since September 1st, 2020 according to the information available on clinicaltrials.gov." - Anonymous Online Contributor

Unverified Answer

Has Triferic been cleared by the FDA?

"Triferic is estimated to be a safe medication, as it has received a score of 3. This is due in part because Triferic is a Phase 3 trial drug, meaning that there are multiple rounds of data supporting both its efficacy and safety." - Anonymous Online Contributor

Unverified Answer

How many total people have signed up to participate in this research project?

"This particular clinical study necessitates 150 individuals that fit the required profile. Locations where this research will take place include Riley Hospital for Children at Indiana University in Indianapolis, Indiana and Loma Linda University Hospital in Loma Linda, California - both of which are operated by the sponsor, Rockwell Medical Technologies, Inc.." - Anonymous Online Contributor

Unverified Answer

Are numerous hospitals in the United States conducting this research?

"A few of the 8 locations where this trial is recruiting patients include Riley Hospital for Children at Indiana University in Indianapolis, Indiana; Loma Linda University Hospital in Loma Linda, California; and Cincinnati Children's Hospital in Cincinnati, Ohio." - Anonymous Online Contributor

Unverified Answer

Are there other documented cases of Triferic's efficacy?

"Triferic's clinical trials are ongoing, with 1 Phase 3 study in progress. Most of these trials are based out of Kansas City, although there are 9 locations total running Triferic trials." - Anonymous Online Contributor

Unverified Answer

Is this the first time this type of trial has been conducted?

"Triferic has been under clinical scrutiny since 2020 when it was first studied by Rockwell Medical Technologies, Inc. Since then, there have been 150 participants in various trials leading up to its Phase 3 approval. Currently, there is one ongoing trial for Triferic being conducted by Rockwell Medical Technologies, Inc.." - Anonymous Online Contributor

Unverified Answer

If I am not yet a senior citizen, can I still qualify for this particular medical research program?

"The age requirements for potential participants in this study are that they must be between 6 months and 17 years old." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.