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General Anesthetic

Inhaled volatile general anesthesia for Anesthesia (THRIVE Trial)

Phase 3
Waitlist Available
Led By Sachin Kheterpal, MD
Research Sponsored by Washington University School of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 11 months
Awards & highlights

THRIVE Trial Summary

This trial is testing whether inhaled anesthesia or intravenous propofol is better for patients undergoing surgery.

Eligible Conditions
  • Anesthesia
  • Surgery
  • Quality of Life
  • Anesthesia Morbidity
  • Depression
  • Anesthesia Complications
  • Circadian Rhythm Disorder
  • Postoperative Pain
  • Surgery Complications
  • Anesthesia Awareness
  • Anesthesia Emergence Delirium
  • Postoperative Nausea

THRIVE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~11 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 11 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Proportion participating
Proportion receiving TIVA
Proportion receiving inhaled anesthesia
Secondary outcome measures
Completeness of data collection

THRIVE Trial Design

2Treatment groups
Active Control
Group I: Inhaled volatile general anesthesiaActive Control1 Intervention
Must administer inhaled agent.
Group II: Propofol total intravenous anesthesia (TIVA)Active Control1 Intervention
No administration of inhaled agent.

Find a Location

Who is running the clinical trial?

Patient-Centered Outcomes Research InstituteOTHER
550 Previous Clinical Trials
29,996,648 Total Patients Enrolled
University of MichiganOTHER
1,796 Previous Clinical Trials
6,377,656 Total Patients Enrolled
Stanford UniversityOTHER
2,393 Previous Clinical Trials
17,340,936 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there a heightened risk associated with anesthesia that is breathed in?

"There is some data supporting efficacy and multiple rounds of safety data, so inhaled volatile general anesthesia received a score of 3."

Answered by AI

Who else is applying?

What state do they live in?
Michigan
How old are they?
18 - 65
What site did they apply to?
University of Michigan
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
THRIVE Feasibility Trial
Michael Avidan 2022. "THRIVE Feasibility Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05346588.
~120 spots leftby Apr 2025
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