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Opioid Analgesic

Lumbar Spine Surgery with Injection for Slipped Disc

Phase 3
Waitlist Available
Research Sponsored by University of Minnesota
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Any adult patient 18 years of age and older who is undergoing surgery for a lumbar spine problem. Common diagnoses in this category would include lumbar disc herniations, spinal stenosis, and spondylolisthesis, but this is not an exhaustive list.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 6 weeks
Awards & highlights

Study Summary

This trial will compare the use of narcotics in two groups of patients: those who receive an injection of ropivacaine, morphine, and epinephrine before surgery, and those who don't. The investigators hope that the injection will reduce narcotic use and length of hospital stay.

Eligible Conditions
  • Slipped Disc
  • Degenerative Disc Disease
  • Spondylolisthesis

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 6 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 6 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Post-operative narcotic use
Secondary outcome measures
Length of hospital stay
Patients' self-reported pain (CAPA) scores

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Lumbar Spine Surgery with InjectionExperimental Treatment3 Interventions
Patients undergoing lumbar spine surgery will receive a peri-incisional injection of pain medications (morphine, epinephrine, and ropivacaine) during their surgery.
Group II: Lumbar Spine Surgery without InjectionActive Control1 Intervention
Patients undergoing lumbar spine surgery will NOT receive a peri-incisional injection of pain medications during their surgery.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Morphine
2013
Completed Phase 4
~2230
Epinephrine
2014
Completed Phase 4
~3940
naropin
2013
N/A
~90

Find a Location

Who is running the clinical trial?

University of MinnesotaLead Sponsor
1,380 Previous Clinical Trials
1,588,745 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Peri-Incisional Drug Injection in Lumbar Spine Surgery
2018. "Peri-Incisional Drug Injection in Lumbar Spine Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03513445.
~0 spots leftby Apr 2025
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