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Corticosteroid

Dexamethasone for Eye Disorders

Phase 3

Recruiting

Led By Oculis Investigative Site

Research Sponsored by Oculis

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day 15

Awards & highlights

Study Summary

This trial will compare the effectiveness and safety of a new eye drop to a placebo in treating inflammation and pain after cataract surgery.

Eligible Conditions

Post-Cataract Surgery Eye Disorders

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 15

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 15

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 15 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of Participants With an Absence of Anterior Chamber Inflammation

Eye pain

Side effects data

From 2013 Phase 4 trial • 122 Patients • NCT01474915

Deep Vein Thrombosis

Cerebrospinal fluid leak

Fever

100%

80%

60%

40%

20%

Study treatment Arm

Ondansetron

Aprepitant

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Active Treatment ArmExperimental Treatment1 Intervention

OCS-01 (Ophthalmic Suspension) - topical use

Group II: Vehicle Placebo ArmPlacebo Group1 Intervention

Vehicle

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Dexamethasone

2007

Completed Phase 4

~2590

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

OculisLead Sponsor

8 Previous Clinical Trials

1,490 Total Patients Enrolled

Oculis Investigative SitePrincipal InvestigatorStudy Principal Investigator

1 Previous Clinical Trials

497 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the common conditions that Dexamethasone treats?

"The eye conditions ophthalmia, sympathetic, and branch retinal vein occlusion can all be treated with Dexamethasone."

Answered by AI

How many individuals are current subjects in this trial?

"Unfortunately, this particular trial is not currently actively recruiting patients. The listing was created on May 1st, 2022 and saw its most recent update on April 28th, 2022. There are presently 507 other clinical trials related to inflammation and 579 trials for Dexamethasone that are actively searching for participants."

Answered by AI

What harmful effects has Dexamethasone been known to cause in patients?

"There is some clinical data supporting the efficacy of dexamethasone, and it has undergone multiple rounds of testing to confirm its safety, so our team at Power estimates that its safety rating is a 3."

Answered by AI

Are there any vacancies in this clinical trial for new participants?

"According to the latest update on clinicaltrials.gov, this particular study is not enrolling patients at the moment. This trial was initially posted on May 1st, 2022 and edited April 28th, 2022. Although research recruitment has ceased for now, there are 1086 other trials you may be eligible for."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

OCS-01: A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

2022. "OCS-01: A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05147233.

All > Cataract