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H2 Receptor Antagonist

Famotidine 20 MG for Pulmonary Arterial Hypertension (REHAB-PH Trial)

Phase 2

Waitlist Available

Led By Peter J Leary, MD, PhD

Research Sponsored by University of Washington

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 0 to 24 weeks

Awards & highlights

REHAB-PH Trial Summary

This trial will test whether the drug famotidine is safe and effective in treating pulmonary arterial hypertension.

Eligible Conditions

Pulmonary Arterial Hypertension
Heart Failure

REHAB-PH Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0 to 24 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0 to 24 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0 to 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Six-minute walk distance

Secondary outcome measures

BNP

Frequency of escalation for PAH focused care (increased diuretics, escalating doses of pulmonary vasodilators, and/or adding additional pulmonary vasodilators)

Health related quality of life (emPHasis-10 questionnaire)

+2 more

Other outcome measures

Cardiopulmonary Exercise Testing (sub-study): Exercise

Cardiopulmonary Exercise Testing (sub-study): Maximal oxygen uptake

Invasive hemodynamics (sub-study): Hemodynamics

+1 more

REHAB-PH Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: FamotidineExperimental Treatment1 Intervention

20mg of oral famotidine (pill) daily Other names: Pepcid

Group II: PlaceboPlacebo Group1 Intervention

Daily oral placebo (pill)

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Famotidine

FDA approved

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of WashingtonLead Sponsor

1,739 Previous Clinical Trials

1,847,848 Total Patients Enrolled

1 Trials studying Pulmonary Arterial Hypertension

60 Patients Enrolled for Pulmonary Arterial Hypertension

National Heart, Lung, and Blood Institute (NHLBI)NIH

3,835 Previous Clinical Trials

47,310,562 Total Patients Enrolled

25 Trials studying Pulmonary Arterial Hypertension

3,071 Patients Enrolled for Pulmonary Arterial Hypertension

Peter J Leary, MD, PhDPrincipal InvestigatorUniversity of Washington

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can people of all ages participate in this research?

"To be eligible for this particular clinical trial, applicants must fall between 18 to 80 years old. There are 61 other trials available for minors and 723 studies open to patients 65 and older."

Answered by AI

Has the Famotidine 20 MG drug been cleared by the FDA?

"Famotidine 20 MG is currently in Phase 2 of clinical trials. While there is some supportive data for its safety, none exists yet to vouch for the efficacy of this medication."

Answered by AI

How many people are enrolled in this research project?

"That is correct. The information available on clinicaltrials.gov indicates that this study is looking for patients right now. This trial was originally posted on May 1st, 2019 and was last updated on November 7th, 2020. The researchers need to enroll 80 people from 1 location."

Answered by AI

Could I possibly qualify to take part in this experiment?

"This study is looking for 80 individuals, both male and female that are aged 18 to 80. These patients must also have pulmonary arterial hypertension and be able to walk a distance of 50 meters with or without the aid of a mobility device."

Answered by AI

Can anyone enroll in this test today?

"That is right, the information available on clinicaltrials.gov reveals that this study is looking for more patients. The listing says that the trial was first posted on May 1st, 2019 and most recently updated on November 7th, 2020. They are hoping to enroll 80 people total from a single location."

Answered by AI

What medical conditions is Famotidine 20 MG regularly employed for?

"Famotidine 20 MG is an effective medication for the treatment of gastritis, heartburn, and zollinger-ellison syndrome."

Answered by AI

Is Famotidine 20 MG a new medication being trialed?

"Currently, there are 15 clinical trials studying the effects of Famotidine 20 MG. 3 of these studies are in Phase 3. The majority of Famotidine 20 MG trials are being conducted out of Pittsburgh, Pennsylvania; though, there are a total of 65 locations running similar studies."

Answered by AI