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Cannabinoid

Cannabis for Pain

Phase 2
Waitlist Available
Research Sponsored by New York State Psychiatric Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 15 days
Awards & highlights

Study Summary

This trial will assess whether tolerance develops to the pain-relieving effects of smoked cannabis, and if so, whether this tolerance is reversed during a period of abstinence.

Eligible Conditions
  • Pain
  • Hyperalgesia
  • Cannabis
  • Drug Tolerance

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 15 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 15 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Cold Pressor Test (CPT) latency
Secondary outcome measures
Change in Cannabis Rating Form (CRF) ratings
Change in Quantitative Sensory Testing-Thermal Temporal Summation (QST-TTS) ratings

Trial Design

1Treatment groups
Experimental Treatment
Group I: Dose A, followed by Dose BExperimental Treatment1 Intervention
On the first full inpatient day (Day 1), participants will smoke one specified strength (Dose A) of cannabis. Days 2-8 will comprise Phase 1, in which a second strength (Dose B) of cannabis will be administered 3x/day. The next 7 days (Day 9-15) will be Phase 2, in which cannabis Dose A will be administered once again, at the same 3 daily time points.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Medical Cannabis
Not yet FDA approved

Find a Location

Who is running the clinical trial?

New York State Psychiatric InstituteLead Sponsor
475 Previous Clinical Trials
153,891 Total Patients Enrolled
2 Trials studying Pain
42 Patients Enrolled for Pain
National Institute on Drug Abuse (NIDA)NIH
2,469 Previous Clinical Trials
2,619,393 Total Patients Enrolled
25 Trials studying Pain
3,263 Patients Enrolled for Pain

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it legal to use Cannabis for medicinal purposes in the United States?

"While there is some evidence supporting the safety of Cannabis, it received a score of 2 because this is only a Phase 2 trial and there is no data yet to support efficacy."

Answered by AI

Have these treatments been used before in a clinical setting?

"To date, there are 35 ongoing investigations into the effects of Cannabis in humans. These trials span 5 nations and 35 cities. The first trial began in 2015 and was completed 3 years later. 61 other studies have been conducted since then."

Answered by AI

Is this study applicable to elderly patients?

"The age bracket for participants in this trial are individuals that are over 21 but younger than 60."

Answered by AI

Might I be able to help with this research by joining the clinical trial?

"To participate in this study, which is investigating the relationship between pain and cannabis use, candidates must be: male or non-pregnant female, 21 to 60 years old, currently using cannabis. A total of 16 people will be enrolled."

Answered by AI

Are new participants being accepted into this research project?

"Yes. The clinical trial is currently looking for 16 patients from 1 location, as indicated by the information on clinicaltrials.gov. This study was originally posted on 8/1/2021 and updated on 8/29/2022."

Answered by AI

Are there other ongoing research projects studying Cannabis?

"35 clinical trials are currently underway to study the effects of cannabis. 3 of those trials have progressed to Phase 3 testing. Most of the trials are based in Hartford, but there are 51 locations total running these studies."

Answered by AI

Who else is applying?

What state do they live in?
Pennsylvania
New Jersey
New York
How old are they?
18 - 65
What site did they apply to?
New York State Psychiatric Institute
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
0
1
3+

Why did patients apply to this trial?

i am looking for alternatives to pain medication including injections. I am a 58 year old with M. S. I am also a patient of Columbia Presbyterian Hospital.
PatientReceived 1 prior treatment
I have degenerative disk disease and would like to offer myself up to be studied for the benefit of those that would benefit from the information.
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans
Caroline A. Arout, Ph.D. 2021. "Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04596644.
~2 spots leftby Aug 2024
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