Treatment for HIV Infections

Phase-Based Progress Estimates
HIV Research Group, San Diego, CA
HIV Infections+1 More
18 - 65
All Sexes
Eligible conditions

Study Summary

This study is evaluating whether a combination of lentinan and ddI is better tolerated than ddI alone.

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Eligible Conditions

  • HIV Infections

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for HIV Infections

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Other trials for HIV Infections

Trial Design

0 Treatment Group

This trial involves 0 different treatment group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: up to 5 years
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly up to 5 years for reporting.

Closest Location

HIV Research Group - San Diego, CA

Eligibility Criteria

This trial is for patients born any sex between 18 and 65 years old. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
HIV seropositivity.
Absolute CD4 count of 200 - 500 cells/mm3.
No active opportunistic infection or Kaposi's sarcoma.
Prior ddI for no longer than 3 months.

Patient Q&A Section

What causes hiv seropositivity?

"Transmission of the virus is via blood transfusions and shared needles. Most HIV infections in the U.S. occur among Blacks, Hispanics, and men who have sex with men; they account for approximately 95% of HIV diagnoses and more than 80% of HIV infections in the U.S." - Anonymous Online Contributor

Unverified Answer

What is hiv seropositivity?

"The probability of being HIVseropositive is much lower if you are Caucasian than a black homosexual male. If you cannot be traced to a country of origin that has a lower prevalence of HIV but which has banned heterosexual activity in the last ten years, then it is likely that you are HIVseropositive. The probability of being HIVseropositive rises significantly for people who have HIV. If you are tested for HIV and you are negative then you can be presumed to be HIVseropositive until you can prove otherwise." - Anonymous Online Contributor

Unverified Answer

What are common treatments for hiv seropositivity?

"HIV disease, in general, is treated similarly to other conditions. Antiretroviral therapy and cART are the standard treatment for both HIV+ and HIV- patients. In addition, most patients who are living with HIV are treated with antiretroviral therapy." - Anonymous Online Contributor

Unverified Answer

Can hiv seropositivity be cured?

"HIV seropositivity is highly associated with reduced immune function, which can cause a decrease in viral clearance. With effective antiretroviral therapy, infectious disease burden is reduced with time, but does not disappear forever." - Anonymous Online Contributor

Unverified Answer

What are the signs of hiv seropositivity?

"There are some symptoms to look for when assessing persons' risk for hiv infection, including pain or swelling in the inner corner of the eye (which sometimes takes a couple of weeks to notice) and fever. A number of symptoms including a dry cough, swollen lymph glands, and neck lymphadenopathy should raise suspicion of possible hiv/aids infection. These symptoms are not present in some patients with other viral infections, so the evaluation of such symptoms can help identify those with hiv infection." - Anonymous Online Contributor

Unverified Answer

How many people get hiv seropositivity a year in the United States?

"Approximately 1.4 million new infections occurred annually because of sexual activity in the United States (0.6% of births). The number of new infections is increasing because of the changing sexual activity patterns of the population. This is due in part to the increased use of condoms at risk situations. Effective prevention can prevent hiv/AIDS." - Anonymous Online Contributor

Unverified Answer

What does treatment usually treat?

"As patients were typically antiretroviral naïve, this observation could not be explained by drug exposure. The use of statins or anti-inflammatory agents was almost twice as likely in HIV-positive patients as in HIV-negative patients. This difference could be statistically significant, and this could explain in part the greater risk of MI and CAD with HIV infection." - Anonymous Online Contributor

Unverified Answer

Does hiv seropositivity run in families?

"We were first to demonstrate significant heritability for hIV-1 in a large family from Zambia. In a recent study, findings indicate the existence of two main factors in the genetic determination of hIV-1 seropositivity: an individual's genetic predisposition and an exposed infected relative. Genetic predisposition plays the major role in the development of HIV-1 infection." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets hiv seropositivity?

"A high-risk sexual lifestyle combined with increasing age may predispose a person to hiv seropositivity; however, the incidence increased to a lesser degree with advancing age; the average age of hiv seropositivity in the high-risk population is likely 20 to 30 years." - Anonymous Online Contributor

Unverified Answer

What is the latest research for hiv seropositivity?

"New strategies for reducing the seroconversion of HIV-1 infected individuals are reviewed. New findings on the role of HIV in the pathogenesis of autoimmunity, immunity and inflammation are also discussed. The impact of hiv seropositivity on the progression from HIV infection to AIDS is also highlighted." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving treatment?

"A recent review identified 13 HIV clinical trials involving adjuvant treatment for [cervical cancer]( or as salvage therapy for previously treated cancers. No single type of treatment was found to be consistently effective in these trials. It is critical to use a systematic review to assess the current body of evidence for adjuvant treatment. Identifying and reporting on clinical trial methodology, such as the treatment design such as randomization, is paramount to the effectiveness of clinical trials. A comprehensive review of all relevant trials should be included at each revision of clinical treatment guidelines." - Anonymous Online Contributor

Unverified Answer

How serious can hiv seropositivity be?

"Recent findings indicate that HIV seronegative persons are not being effectively screened, regardless of their sexual behavior, use of condoms, or history of STD. These data substantiate the need for improved monitoring of the HIV seronegative population." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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