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Nucleoside Reverse Transcriptase Inhibitor

Antiretroviral Therapy Regimen for HIV

Phase 3
Waitlist Available
Research Sponsored by Glaxo Wellcome
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is testing whether the addition of GW433908 to the existing drug regimen of ABC/3TC can improve viral response in patients who have not yet taken ART drugs.

Who is the study for?
This trial is for individuals at least 13 years old with HIV who haven't taken ART drugs, or only NRTI for less than 4 weeks. They must have a viral load of over 1,000 copies/ml and agree to use barrier contraception. Excluded are those with recent acute HIV complications, substance abuse issues, serious health conditions like diabetes or heart problems, pregnant or breastfeeding women, and anyone treated recently with certain medications.Check my eligibility
What is being tested?
The study aims to compare the effectiveness of GW433908/ritonavir (RTV) versus nelfinavir (NFV), both combined with abacavir/lamivudine in patients new to antiretroviral therapy. It will measure how well these drug combinations control the amount of virus in the blood.See study design
What are the potential side effects?
Potential side effects may include digestive issues such as nausea and diarrhea, liver problems like hepatitis, allergic reactions including skin rashes or more severe responses, changes in body fat distribution and possible increases in cholesterol levels.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Find a Location

Who is running the clinical trial?

Glaxo WellcomeLead Sponsor
120 Previous Clinical Trials
23,806 Total Patients Enrolled

Media Library

Abacavir (Nucleoside Reverse Transcriptase Inhibitor) Clinical Trial Eligibility Overview. Trial Name: NCT00009061 — Phase 3
Human Immunodeficiency Virus Infection Research Study Groups:
Human Immunodeficiency Virus Infection Clinical Trial 2023: Abacavir Highlights & Side Effects. Trial Name: NCT00009061 — Phase 3
Abacavir (Nucleoside Reverse Transcriptase Inhibitor) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00009061 — Phase 3
Human Immunodeficiency Virus Infection Patient Testimony for trial: Trial Name: NCT00009061 — Phase 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are subjects still being accepted for participation in this trial?

"No, this particular trial is not currently looking for patients. Although, it is worth mentioning that there are 495 other clinical trials that are still recruiting patients."

Answered by AI

Does this treatment present any risks for patients?

"This clinical trial is in Phase 3, which indicates that while there is some efficacy data, more rounds of testing are needed to confirm safety. Therefore, the Power team gave this treatment a score of 3."

Answered by AI

Does this research include middle-aged or elderly individuals?

"This trial is only for patients aged 13+, which differentiates it from 109 other studies for minors and 364 studies for older adults."

Answered by AI

Can I join this clinical trial?

"This trial is looking for 624 hiv positive participants aged 13 and up. To meet the criteria for this study, potential patients must: Be above the age of 13 ( parental/guardian consent needed if under 18), Use a reliable form of birth control during the study period (hormonal birth control will not be accepted), if able to have children., Have received less than 4 weeks treatment with any nucleoside reverse transcriptase inhibitor (NRTI) and have never received any nonnucleoside reverse transcriptase inhibitor (NNRTI) or protease inhibitor (PI). Mothers who have previously received 1 dose of the"

Answered by AI

Who else is applying?

What state do they live in?
New York
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

To help with the research.
PatientReceived no prior treatments

What questions have other patients asked about this trial?

What is the incentive for this trial?
PatientReceived 2+ prior treatments
~26 spots leftby Apr 2025