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Vitamin

Vitamin C infusion (ascorbic acid) for Sepsis (CITRIS-AH Trial)

Phase 2
Waitlist Available
Led By Arun J Sanyal, MD
Research Sponsored by Virginia Commonwealth University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 168 hours
Awards & highlights

CITRIS-AH Trial Summary

This study is evaluating whether vitamin C may help treat alcoholic hepatitis and sepsis.

Eligible Conditions
  • Sepsis
  • Alcoholic Hepatitis

CITRIS-AH Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 168 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 168 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Model for End Stage Liver Disease (MELD) Score
Secondary outcome measures
Change in Alanine Aminotransferase (ALT) Level
Change in Albumin
Change in Alkaline Phosphatase
+11 more

CITRIS-AH Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Vitamin C infusion (ascorbic acid)Active Control2 Interventions
Vitamin C 200mg/kg/24hours administered in four doses per day (given every 6 hours)
Group II: PlaceboPlacebo Group1 Intervention
Dextrose 5% in water 50 milliliters (mL) administered intravenously every 6 hours

Find a Location

Who is running the clinical trial?

Virginia Commonwealth UniversityLead Sponsor
699 Previous Clinical Trials
22,885,025 Total Patients Enrolled
5 Trials studying Sepsis
9,034 Patients Enrolled for Sepsis
National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
802 Previous Clinical Trials
1,365,425 Total Patients Enrolled
1 Trials studying Sepsis
37,986 Patients Enrolled for Sepsis
Arun J Sanyal, MDPrincipal InvestigatorVirginia Commonwealth University
3 Previous Clinical Trials
1,060 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis
2019. "Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03829683.
~3 spots leftby Apr 2025
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