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Beta Blocker

Travoprost Intraocular Implant, high elution for Open-Angle Glaucoma

Phase 2
Waitlist Available
Research Sponsored by Glaukos Corporation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Open angle glaucoma
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up post-op through month 36
Awards & highlights

Study Summary

This study is evaluating whether a higher dose of the Travoprost Intraocular implant is more effective than a lower dose.

Eligible Conditions
  • Open-Angle Glaucoma

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~post-op through month 36
This trial's timeline: 3 weeks for screening, Varies for treatment, and post-op through month 36 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
IOP (mmHg) Change From Baseline at Week 12
Other outcome measures
Severe Adverse Events

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Travoprost Intraocular Implant, low elutionExperimental Treatment1 Intervention
This implant will be surgically implanted and elute travoprost, a prostaglandin.
Group II: Travoprost Intraocular Implant, high elutionExperimental Treatment1 Intervention
This implant will be surgically implanted and elute travoprost, a prostaglandin.
Group III: Timolol Maleate Ophthalmic Solution, 0.5%Active Control1 Intervention
Timolol, a beta blocker, will be dosed twice daily
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Travoprost
FDA approved
Travoprost
FDA approved

Find a Location

Who is running the clinical trial?

Glaukos CorporationLead Sponsor
65 Previous Clinical Trials
8,886 Total Patients Enrolled
Kerry Stephens, O.D.Study ChairGlaukos Corporation
4 Previous Clinical Trials
1,665 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution
2016. "Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02754596.
~17 spots leftby Apr 2025
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