← Back to Search

Surgery

Trabeculectomy vs. Argon Laser Trabeculoplasty for Glaucoma

Phase 3

Waitlist Available

Research Sponsored by National Eye Institute (NEI)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Men and women between the ages of 35 and 80 with open-angle glaucoma that was not successfully controlled by medication were eligible for enrollment

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial is testing the long-term effects of two common glaucoma treatments, trabeculectomy and argon laser trabeculoplasty, in people who haven't been helped by other medical treatments.

Who is the study for?

This trial is for men and women aged 35-80 who have open-angle glaucoma that hasn't improved with medication. It's not suitable for those who don't meet the age requirement or have different types of glaucoma.Check my eligibility

What is being tested?

The study is looking at long-term results from two treatments after initial meds fail: trabeculectomy (surgery to drain fluid) and argon laser trabeculoplasty (laser treatment to improve drainage).See study design

What are the potential side effects?

Possible side effects include discomfort, redness, or infection in the eye from surgery, and temporary increased eye pressure or vision changes from the laser treatment.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

National Eye Institute (NEI)Lead Sponsor

546 Previous Clinical Trials

1,401,928 Total Patients Enrolled

41 Trials studying Glaucoma

13,401 Patients Enrolled for Glaucoma

Media Library

Trabeculectomy (Surgery) Clinical Trial Eligibility Overview. Trial Name: NCT00000148 — Phase 3

Glaucoma Clinical Trial 2023: Trabeculectomy Highlights & Side Effects. Trial Name: NCT00000148 — Phase 3

Trabeculectomy (Surgery) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00000148 — Phase 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are we still able to sign up for this experiment?

"Information available on clinicaltrials.gov suggests that this trial is not, at present, looking for new patients to enroll. The study was first posted on April 1st 1988 and edited most recently on June 2nd 2006. There are, however, 205 other trials currently underway which are recruiting participants."

Answered by AI

Does the age limit for this test extend past 75 years old?

"Patients that meet the age requirement of 35-80 years old are eligible for this trial. There are 23 other studies available for patients under 18 and 190 trials for seniors above the age of 65."

Answered by AI

Could you please outline the risks associated with this treatment plan?

"There is some efficacy data from Phase 3 trials as well as multiple rounds of safety data, so our team at Power has given this treatment a score of 3 for safety."

Answered by AI

At how many facilities is this research being conducted?

"There are a total of 13 clinical sites hosting this trial. They are situated in Chicago, Southfield, Atlanta and 10 other cities. If you hope to enroll, it is best to choose the location nearest to you so that travel isn't excessive."

Answered by AI

Recent research and studies

Controlled Clinical TrialsJournal

The Advanced Glaucoma Intervention Study (AGIS): 1. Study Design and Methods and Baseline Characteristics of Study Patients

“The Advanced Glaucoma Intervention Study (AGIS): 1. Study Design and Methods and Baseline Characteristics of Study Patients”. 1994. “The Advanced Glaucoma Intervention Study (AGIS): 1. Study Design and Methods and Baseline Characteristics of Study Patients”. Controlled Clinical Trials. Elsevier BV. doi:10.1016/0197-2456(94)90046-9.

OphthalmologyJournal

Reliability of Visual Fields in AGIS

Lempert, Philip. 1995. “Reliability of Visual Fields in AGIS”. Ophthalmology. Elsevier BV. doi:10.1016/s0161-6420(95)31014-7.

OphthalmologyJournal

The Advanced Glaucoma Intervention Study (AGIS): 3. Baseline Characteristics of Black and White Patients

“The Advanced Glaucoma Intervention Study (AGIS): 3. Baseline Characteristics of Black and White Patients”. 1998. “The Advanced Glaucoma Intervention Study (AGIS): 3. Baseline Characteristics of Black and White Patients”. Ophthalmology. Elsevier BV. doi:10.1016/s0161-6420(98)97012-9.

OphthalmologyJournal