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Herbal Supplement

Milk Thistle for Gambling Addiction

Phase 2
Waitlist Available
Led By Jon E Grant, JD, MD, MPH
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up once every two weeks for the 8 weeks of the study
Awards & highlights

Study Summary

This trial will test if silymarin, a substance derived from milk thistle, is an effective and safe treatment for gambling disorder.

Eligible Conditions
  • Gambling Addiction

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~once every two weeks for the 8 weeks of the study
This trial's timeline: 3 weeks for screening, Varies for treatment, and once every two weeks for the 8 weeks of the study for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Yale Brown Obsessive Compulsive Scale Modified for Pathological Gambling (PG-YBOCS)
Secondary outcome measures
Clinical Global Impression-Improvement and Severity scales (CGI)
Gambling Symptom Assessment Scale (G-SAS)
Hamilton Anxiety Rating Scale (HAM-A)
+4 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Milk ThistleActive Control1 Intervention
Capsule form, 150mg BID to 300mg BID
Group II: PlaceboPlacebo Group1 Intervention
Matched dosage of milk thistle daily.

Find a Location

Who is running the clinical trial?

University of ChicagoLead Sponsor
1,004 Previous Clinical Trials
819,734 Total Patients Enrolled
Jon E Grant, JD, MD, MPHPrincipal InvestigatorUniversity of Chicago
7 Previous Clinical Trials
834 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Milk Thistle in Pathological Gambling
2015. "Milk Thistle in Pathological Gambling". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02337634.
~4 spots leftby Apr 2025
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