Your session is about to expire
← Back to Search
NT-I7 for Esophageal Cancer
Study Summary
This trial is testing a new cancer treatment combining NT-I7 with nivolumab to see if it is safe and effective in treating gastric or gastro-esophageal junction (GEJ) or esophageal adenocarcinoma (EAC). The study will first assess safety in escalating doses to find the maximum tolerated dose (MTD) or the recommended Phase 2 dose (RP2D). If the treatment is well tolerated, the study will then continue in Phase 2 to preliminary assess the antitumor activity and long-term survival of the treatment combination.
- Esophageal Cancer
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Frequently Asked Questions
Are there any vacancies for participants in this trial?
"As suggested by the data found on clinicaltrials.gov, this trial is actively recruiting participants. The listing was first published on January 21st 2021 and has since been revised once more as of September 27th 2022."
How widely distributed is the trial taking place in North America?
"Currently, this medical trial is operating at 4 sites located in Louisville, Fort Worth and Houston as well as other cities. To reduce the need for travel during participation, it is recommended to choose a location closest to your residence."
Is there any prior research regarding NT-I7?
"Currently, there are 728 clinical studies underway that examine the effectiveness of NT-I7. 82 trials have been deemed Phase 3 and are being conducted at 40292 locations across the world with a concentration in Basel, BE."
To what extent is participation in this experiment widespread?
"Affirmative. Clinicaltrials.gov documents corroborate that this trial, which was originally announced on January 21st 2021, is actively enrolling patients. Approximately 68 individuals must be recruited from four different medical institutions."
What clinical scenarios is NT-I7 usually prescribed for?
"NT-I7 is conventionally used to treat cancerous tumors. It has shown promise in the treatment of difficult cancers such as melanoma, squamous cell carcinoma and metastatic esophageal adenocarcinoma."
How hazardous are the effects of NT-I7 for participants?
"Due to the lack of efficacy data, NT-I7 was assigned a score of 2 on our safety scale. However, there is clinical evidence that it maintains a certain level of safety when used in Phase 2 trials."
Is this an untested or pioneering experiment?
"Since 2012, NT-I7 has been the subject of numerous studies. The inaugural trial was sponsored by Ono Pharmaceutical Co. Ltd and incorporated 659 participants. This data set gained phase 1 & 2 drug approval, leading to an additional 728 active trials in 2354 cities across 49 nations presently."
Share this study with friends
Copy Link
Messenger