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Procedure

Endolumenal Partial Myotomy for Esophageal Motility Disorder

Phase 2

Waitlist Available

Research Sponsored by The Oregon Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Ability to undergo general anesthesia

Candidate for elective Heller myotomy

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 month

Awards & highlights

Study Summary

This trial is testing whether a new, minimally invasive treatment for achalasia and esophageal spasm is effective.

Who is the study for?

This trial is for individuals who can undergo general anesthesia and are candidates for elective Heller myotomy, a surgical procedure to treat esophageal motility disorders. Participants must be able to give informed consent. Those with previous chest or esophageal surgery, or contraindications for an upper GI endoscopy cannot join.Check my eligibility

What is being tested?

The study is testing a new therapeutic approach called flexible endoscopic myotomy as an alternative to invasive surgery for treating achalasia and esophageal spasm, conditions where the lower part of the esophagus doesn't relax properly.See study design

What are the potential side effects?

Potential side effects may include discomfort at the site of intervention, risk of infection from the procedure, possible bleeding or perforation during myotomy, and temporary difficulty swallowing post-procedure.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I can safely be put under general anesthesia.

Select...

I am a candidate for surgery to treat swallowing difficulties.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 month

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 month

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Esophageal Function Tests

Secondary outcome measures

Quality of life score

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

The Oregon ClinicLead Sponsor

13 Previous Clinical Trials

1,470 Total Patients Enrolled

Media Library

Endolumenal Partial Myotomy (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT01302301 — Phase 2

Esophageal Motility Disorder Research Study Groups:

Esophageal Motility Disorder Clinical Trial 2023: Endolumenal Partial Myotomy Highlights & Side Effects. Trial Name: NCT01302301 — Phase 2

Endolumenal Partial Myotomy (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01302301 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are geriatric patients eligible to participate in this experiment?

"This clinical trial is enlisting participants who are older than the age of consent and younger than 85 years old."

Answered by AI

Has this intervention been given the go-ahead by the Food and Drug Administration?

"Although efficacy is yet to be documented, some clinical evidence has been amassed in support of its safety. Thus, we have rated this treatment with a 2 on our risk scale from 1-3."

Answered by AI

Which patient profiles best meet the qualifications for this clinical research?

"Recruitment for this clinical trial is underway, targeting 20 patients aged between 18 and 85 who have been diagnosed with nutcracker esophagus. Those hoping to participate must be eligible for elective Heller myotomy, able to undergo general anesthesia, and capable of giving informed consent."

Answered by AI

Is enrollment for this clinical experiment currently available?

"Clinicaltrials.gov confirms that this particular trial, which was initially posted on January 1st 2011 and last updated February 25th 2011, is not looking for patients presently. Nonetheless, there are 7 other studies actively enrolling participants now."

Answered by AI

Recent research and studies

EndoscopyJournal

Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia

Inoue, H., H. Minami, Y. Kobayashi, Y. Sato, M. Kaga, M. Suzuki, H. Satodate, N. Odaka, H. Itoh, and S. Kudo. 2010. “Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia”. Endoscopy. Georg Thieme Verlag KG. doi:10.1055/s-0029-1244080.

EndoscopyJournal

Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia

clinicaltrials.govStudy

Endolumenal Partial Myotomy for Esophageal Motility Disorders

2011. "Endolumenal Partial Myotomy for Esophageal Motility Disorders". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01302301.

All > Paid Studies Oregon