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Brachytherapy

Carboplatin for Endometrial Cancer

Phase 2
Waitlist Available
Led By Kathleen Moore, MD
Research Sponsored by University of Oklahoma
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 2 years
Awards & highlights

Study Summary

This trial is testing a new treatment for endometrial cancer that involves radiation and chemotherapy.

Eligible Conditions
  • Endometrial Cancer
  • Serous Cystadenocarcinoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Patients Completing the Protocol
Secondary outcome measures
Contributing Cause of Death
Frequency of Adverse Events Related to Acute Toxicity During Treatment
Overall Survival
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Vaginal Cuff Brachytherapy + ChemotherapyExperimental Treatment3 Interventions
Vaginal cuff brachytherapy followed by Carboplatin (AUC 6) on day 1and Paclitaxel 80 mg/m2 IV over 1 hour days 1, 8, and 15 X 3 total cycles
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Vaginal Cuff Brachytherapy
2017
Completed Phase 2
~70
Carboplatin
FDA approved
Paclitaxel
FDA approved

Find a Location

Who is running the clinical trial?

University of OklahomaLead Sponsor
455 Previous Clinical Trials
97,574 Total Patients Enrolled
6 Trials studying Endometrial Cancer
302 Patients Enrolled for Endometrial Cancer
Kathleen Moore, MDPrincipal InvestigatorStephenson Cancer Center
8 Previous Clinical Trials
406 Total Patients Enrolled
2 Trials studying Endometrial Cancer
159 Patients Enrolled for Endometrial Cancer

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals have signed up for participation in this medical experiment?

"This medical trial is not currently seeking enrollees. Despite being initially posted on October 2nd 2017 and last updated on August 13th 2021, no additional patients are needed at this time. However, there are presently 285 studies actively recruiting those suffering from papillary serous and 1174 trials using Paclitaxel that require volunteers to participate."

Answered by AI

Is this research open to participants who are below the age of 80?

"The requisite age range for this trial is between 18 and 99. However, there are 94 trials specifically tailored to participants below the legal age of consent and 1390 studies available to seniors over 65 years old."

Answered by AI

Is there an opportunity to be included in this trial?

"Eligibility requirements for this trial include being aged between 18 and 99 with a diagnosis of papillary serous. Currently, the study is accepting 39 participants across its sites."

Answered by AI

Has Paclitaxel attained regulatory approval from the Food and Drug Administration?

"Paclitaxel is deemed to be of moderate safety according to our team at Power. This assessment was made due to the Phase 2 status, meaning there exists evidence for its security but not yet efficacy."

Answered by AI

What illness can Paclitaxel be prescribed to alleviate?

"Paclitaxel has the potential to treat malignant melanoma, neoplasm metastasis and non-Hodgkin's lymphoma."

Answered by AI

What other research projects have focused on Paclitaxel?

"Paclitaxel is the focus of 1174 currently active clinical trials, with 332 of these in their final stage. Shanghai has a concentration of Paclitaxel-related studies; however, 66508 sites worldwide are conducting various experiments concerning this medication."

Answered by AI

Is there a recruitment process currently underway for this trial?

"Unfortunately, this medical trial hasn't been actively recruiting since its last update on August 13th 2021. For those looking for similar trials, there are 285 studies currently searching for patients with papillary serous and 1174 that involve Paclitaxel therapies."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Vaginal Cuff Brachytherapy Followed by Chemotherapy in Endometrial Cancer
2017. "Vaginal Cuff Brachytherapy Followed by Chemotherapy in Endometrial Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03189446.
~5 spots leftby Apr 2025
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