This trial found that postpartum prophylactic administration of hydrochlorothiazide (HCTZ) may be effective in preventing relapse of preeclampsia or gestational hypertension.
- Postpartum Pregnancy-Induced Hypertension (PPIH)
- Superimposed Preeclampsia
- Pregnancy-Induced Hypertension
- Postpartum preeclampsia
2 Primary · 6 Secondary · Reporting Duration: 1-6 weeks postpartum
Awards & Highlights
2 Treatment Groups
Hydrochlorothiazide 50mg Tablet
1 of 2
1 of 2
612 Total Participants · 2 Treatment Groups
Primary Treatment: Hydrochlorothiazide 50mg Tablet · Has Placebo Group · Phase 3
Who is running the clinical trial?
Age 18 - 50 · Female Participants · 0 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
How many patients are enrolled in this research project?
"That is correct. The listing on clinicaltrials.gov confirms that this study, which was first advertised on November 21st 2017, is still recruiting patients. They are looking for 612 people to participate at 3 different locations." - Anonymous Online Contributor
What are some of the dangers associated with taking Hydrochlorothiazide 50mg Tablet?
"Hydrochlorothiazide 50mg Tablet is classified as a Phase 3 drug, meaning that there is both efficacy and safety data available. Our team has rated its safety as a 3 out of 3." - Anonymous Online Contributor
Are any slots still available for participants in this trial?
"Indeed, the clinical trial is still open and recruiting patients. According to the information on clinicaltrials.gov, the study was first posted on 11/21/2017, with the most recent update being made 8/18/2022. They are looking for 612 participants total, which will be recruited from 3 sites." - Anonymous Online Contributor
What is the goal of this clinical trial?
"The primary outcome of this study, which will take place in the 6 weeks post-partum, is the Need for additional antihypertensive therapy. Additionally, we will measure Use of resources (hospital stay, postpartum clinic or emergency room visit within 4-6 weeks of delivery, need for imaging or other invasive procedures), Total Additional doses of anti-hypertensive therapy (addition of total doses that patient received in the postpartum period), and Length of hospital stay (days that patient required to be in-house in the postpartum period) as secondary outcomes." - Anonymous Online Contributor
Can I join this clinical trial?
"The ideal candidate for this study is a woman aged 18-50 who has been diagnosed with pre-eclampsia. A total of 612 participants are needed." - Anonymous Online Contributor
What are some common reasons why people take Hydrochlorothiazide 50mg Tablets?
"Hydrochlorothiazide 50mg Tablet is often used to counteract sodium retention, but it can also be helpful in managing edema, when other therapies have been ineffective, and for patients who do not respond well to blood pressure medication." - Anonymous Online Contributor
Are there other research papers that focus on Hydrochlorothiazide 50mg Tablet?
"There are currently 12 ongoing clinical trials studying the effects of Hydrochlorothiazide 50mg Tablets. 5 of those trials are in their third and final phase. Most of the trial locations for this medication are centred around Kansas City, Kansas; though, there are 80 total locations running these studies." - Anonymous Online Contributor
If a septuagenarian meets the other requirements, are they eligible for this research project?
"The parameters for this study only allow patients aged 18 to 50. However, there are 66 other clinical trials for minors and 739 for seniors." - Anonymous Online Contributor