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Behavioral Intervention

Diabetes Genetic Counseling for Obesity (GC/LC Trial)

Phase 2
Waitlist Available
Led By Richard W Grant, MD MPH
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months
Awards & highlights

GC/LC Trial Summary

This study will examine the impact diabetes genetic counseling on patient motivation and disease prevention behaviors among subjects with pre-diabetes. Intervention subjects will be provided with their individual diabetes genotype risk score derived from aggregating the combined results of 37 diabetes risk-associated genetic loci. Controls will not be tested. All subjects will be enrolled in a 12-week diabetes prevention program.

Eligible Conditions
  • Obesity
  • Metabolic Syndrome
  • Prediabetes

GC/LC Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
stage of change
Secondary outcome measures
program attendance

GC/LC Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Diabetes Genetic CounselingExperimental Treatment1 Intervention
Subjects will have been genotyped and will received genetic counseling based on their results
Group II: No Genotyping or CounselingPlacebo Group1 Intervention
Patients will not be genotyped and will therefore not receive genetic counseling

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,932 Previous Clinical Trials
13,198,405 Total Patients Enrolled
71 Trials studying Obesity
291,094 Patients Enrolled for Obesity
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,359 Previous Clinical Trials
4,315,405 Total Patients Enrolled
447 Trials studying Obesity
588,938 Patients Enrolled for Obesity
Richard W Grant, MD MPHPrincipal InvestigatorMassachusetts General Hospital
6 Previous Clinical Trials
2,943 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Diabetes CareJournal
Personalized Genetic Risk Counseling to Motivate Diabetes Prevention
Grant, Richard W., Kelsey E. O’Brien, Jessica L. Waxler, Jason L. Vassy, Linda M. Delahanty, Laurie G. Bissett, Robert C. Green, et al.. 2012. “Personalized Genetic Risk Counseling to Motivate Diabetes Prevention”. Diabetes Care. American Diabetes Association. doi:10.2337/dc12-0884.
clinicaltrials.govStudy
Genetic Counseling and Lifestyle Change for Diabetes Prevention
2009. "Genetic Counseling and Lifestyle Change for Diabetes Prevention". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01034319.
All > Prevention > Diabetes
~6 spots leftby Apr 2025
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