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Topical Cream

EB01 Cream 2.0% for Allergic Contact Dermatitis

Phase 2
Waitlist Available
Research Sponsored by Edesa Biotech Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up days 15, 29, 59, 89, and 119
Awards & highlights

Study Summary

This trial will test a new cream to see if it is safe and effective in treating people with a chronic allergic skin condition.

Eligible Conditions
  • Allergic Contact Dermatitis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~days 15, 29, 59, 89, and 119
This trial's timeline: 3 weeks for screening, Varies for treatment, and days 15, 29, 59, 89, and 119 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mean percent change from baseline in the Contact Dermatitis Severity Index (CDSI)
Secondary outcome measures
Change from baseline in Dermatology Life Quality Index (DLQI)
Mean percent change from baseline in Body Surface Area (BSA) affected with chronic allergic contact dermatitis
Mean percent change from baseline in CDSI
+3 more
Other outcome measures
Tolerability assessed using a numerical rating scale
Treatment-emergent adverse events (TEAEs)

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: EB01 Cream 2.0%Experimental Treatment1 Intervention
EB01 Cream containing 2.0% EB01 w/w applied BID
Group II: EB01 Cream 1.0%Experimental Treatment1 Intervention
EB01 Cream containing 1.0% EB01 w/w applied BID
Group III: EB01 Cream 0.2%Experimental Treatment1 Intervention
EB01 Cream containing 0.2% EB01 w/w applied BID
Group IV: EB01 Cream PlaceboActive Control1 Intervention
EB01 Cream containing 0% EB01 w/w applied BID

Find a Location

Who is running the clinical trial?

JSS Medical Research Inc.Industry Sponsor
18 Previous Clinical Trials
5,369 Total Patients Enrolled
Edesa Biotech Inc.Lead Sponsor
1 Previous Clinical Trials
644 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the demographic for this trial inclusive of individuals aged 70 or older?

"Candidates aged between 18 and 70 are viable for this trial; however, there is an additional 96 trials available to those below the age of majority, as well 156 studies appropriate for seniors above 65."

Answered by AI

Are there any vacancies available in this clinical experiment?

"As per clinicaltrials.gov, this particular medical trial is no longer enrolling patients; the initial listing was posted on October 15th 2019 and last updated on September 9th 2022. Nevertheless, there are 221 other trials actively searching for participants at present."

Answered by AI

How many sites are hosting the research for this experiment?

"Across the United States of America, 14 different clinical trial sites are currently in operation. Notable locations include Bexley Dermatology, The Dermatology Clinic found in Baton Rouge and Associated Skin care Specialists situated in Fridley."

Answered by AI

Could you provide an assessment of the safety profile for EB01 Cream 2.0%?

"Due to the Phase 2 trial status of EB01 Cream 2.0%, our team at Power deemed its safety level as a score of two, implying that some evidence exists for its security but none yet for efficacy."

Answered by AI

Is enrollment available for this medical experiment?

"This clinical trial is enrolling up to 126 individuals in the 18-70 age bracket who have allergic contact dermatitis. Additional requirements include: men and women of consenting age, those considered biologically able to bear children must use a reliable form contraception for at least 4 weeks pre and post study product application, surgical sterilization (hysterectomy/oophorectomy), cessation of menses for 12 months accompanied by an appropriate FSH test confirming nonchildbearing potential, male participants engaging in intercourse requiring contraceptive measures from Day 1 until 4 weeks after last study administration, negative pregnancy test for female childbearing potentials prior to screening"

Answered by AI

Who else is applying?

What state do they live in?
New Jersey
New York
How old are they?
18 - 65
What site did they apply to?
ColumbiaDoctors Midtown
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
~23 spots leftby Apr 2025