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ALTO-100 PO tablet for Post-Traumatic Stress Disorder

Phase 2
Waitlist Available
Research Sponsored by Alto Neuroscience
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured 5 times over 8 weeks
Awards & highlights

Study Summary

This trial will help researchers understand how well ALTO-100 works in people with mild-to-moderate Alzheimer's disease.

Eligible Conditions
  • Post-Traumatic Stress Disorder
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured 5 times over 8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured 5 times over 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Participants With Clinically Significant Laboratory Abnormalities as a Measure of Safety and Tolerability of ALTO-100
Number of Participants With Clinically Significant Vital Signs Abnormalities as a Measure of Safety and Tolerability of ALTO-100
Number of Participants with Adverse Events (AEs) as a Measure of Safety and Tolerability of ALTO-100
+3 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: ALTO-100Experimental Treatment1 Intervention
ALTO-100 PO tablet, daily dosing 8 weeks
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ALTO-100 PO tablet
2021
Completed Phase 2
~250

Find a Location

Who is running the clinical trial?

Alto NeuroscienceLead Sponsor
7 Previous Clinical Trials
726 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this survey accommodate participants of a younger age bracket?

"This particular research study necessitates that participants are aged between 18 and 69. For patients below the age of consent, there are 434 studies available to them whereas 1668 can be found for seniors past 65 years old."

Answered by AI

Has the study been implemented on a nation-wide scale in America?

"Patients can find this particular trial at Site 137 in Noblesville, Indiana and Site 142 in Lincoln, Nebraska. Additionally, there are 21 other sites scattered about the country - including one located in Mather California."

Answered by AI

Has the ALTO-100 PO tablet been given clearance by the FDA?

"Our team at Power gives ALTO-100 PO tablet a rating of 2 on the safety scale, as it has not gone through Phase 3 trials yet and thus lacks clinical evidence to support its efficacy."

Answered by AI

Are there any opportunities for participants to join this research endeavor?

"As detailed on clinicaltrials.gov, this particular research has stopped accepting participants; the initial post was made December 9th 2021 and last updated October 21st 2022. Despite this announcement, 2310 other medical studies are currently recruiting patients to join their trials."

Answered by AI

To whom is enrollment in this research endeavor open?

"This research initiative is seeking 245 individuals between the ages of 18 and 69 who are suffering from melancholia. In order to be considered, participants must meet additional criteria such as a diagnosis of moderate to severe major depressive disorder (MDD) or post-traumatic stress disorder (PTSD). Additionally, they should either not be taking an antidepressant medication or have been on one for at least 6 weeks without any dose modifications in the past 2 weeks. Furthermore, applicants need to commit to fulfilling all associated study assessments and procedures; this includes abstaining from pregnancy or breastfeeding during their enrollment period as well as throughout its duration."

Answered by AI

Who else is applying?

What site did they apply to?
Site 116
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
3+

What questions have other patients asked about this trial?

What are the side effects of the drug?
PatientReceived no prior treatments

Why did patients apply to this trial?

No, I’m struggling with my situation and being stuck I would like to find out and stop feeling like I procrastinate everything. I need help.
PatientReceived no prior treatments
~73 spots leftby Apr 2025