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Anti-inflammatory

Acebilustat for Coronavirus (COPPS Trial)

Phase 2
Waitlist Available
Led By Angela Rogers, MD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 28 days
Awards & highlights

COPPS Trial Summary

This trial is designed to find COVID-19 treatments that work for people who are not yet sick enough to require hospitalization.

Eligible Conditions
  • Coronavirus

COPPS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~28 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 28 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
For Clinical Domain: Time-to-sustained-resolution
Secondary outcome measures
For the Viral Domain: Change in Viral Shedding
Number of Participants That Developed Antibodies to SARS-CoV-2
Number of Participants With SARS-CoV-2 Related Hospitalizations, Emergency Department (ED) Visits, or Death in Outpatients With COVID-19 Disease.
+3 more

Side effects data

From 2023 Phase 2 trial • 120 Patients • NCT04662060
2%
Nausea
100%
80%
60%
40%
20%
0%
Study treatment Arm
Placebo
Acebilustat

COPPS Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: AcebilustatExperimental Treatment1 Intervention
Participants are randomized to receive acebilustat for 28 days.
Group II: Matching PlaceboPlacebo Group1 Intervention
Participants are randomized to receive placebo to match acebilustat for 28 days.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acebilustat
2021
Completed Phase 2
~250

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,395 Previous Clinical Trials
17,341,235 Total Patients Enrolled
Angela Rogers, MDPrincipal InvestigatorStanford University
Joseph Levitt, MD, MSPrincipal InvestigatorStanford University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What other drugs has Acebilustat been tested with in previous clinical trials?

"There are presently 2 ongoing studies involving Acebilustat. Of these, 0 are in the final Phase 3 stage. Most of the research is based at Stanford University; however, there are also 3 other clinical trial sites."

Answered by AI

How many people have been recruited for this clinical trial thus far?

"Unfortunately, this particular clinical trial is no longer admitting patients. The study was originally posted on April 23rd, 2021 but was last updated on September 12th, 2022. There are currently 1137 other trials involving covid-19 that are still enrolling patients as well as 2 other trials for Acebilustat."

Answered by AI

What are the risks that come with taking Acebilustat?

"Because there is only data supporting safety and no efficacy for Acebilustat, it received a score of 2."

Answered by AI

If a patient is over the age of 40, can they still enroll in this clinical trial?

"Eligibility for this clinical study requires that potential patients are aged 18 to 80. However, there are 145 other trials available for minors and 988 different studies open to people over the age of 65."

Answered by AI

To whom does this chance to be a research subject apply?

"This study is seeking 120 individuals that have contracted covid-19 and are between 18-80 years old. There are certain additional requirements that must be met in order to qualify which are as follows: At the start of the trial, applicants must have at least two symptoms with a mild or higher severity score OR one symptom with a moderate severity score., The individual's first symptom related to COVID-19 should have occurred within the week prior to being randomized for the study., Must be an outpatient, Other inclusion criteria specific to the investigational product that may, in the eyes of the investigator, be deemed necessary.."

Answered by AI

Are investigators still looking for people to enroll in this clinical trial?

"Unfortunately, this particular trial is not currently seeking participants. Although, it was first posted on April 23rd 2021 and edited most recently on September 12th 2022. For those looking for other studies, there are 1137 trials actively recruiting patients with covid-19 and 2 studies for Acebilustat that still need participants."

Answered by AI
~30 spots leftby Apr 2025