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Silmitasertib for Coronavirus Infection (CX4945 Trial)

Phase 2
Waitlist Available
Research Sponsored by University of Arizona
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up days 4, 8, 11, 14, and 28
Awards & highlights

CX4945 Trial Summary

This study is evaluating whether a drug may help treat severe acute respiratory syndrome.

Eligible Conditions
  • Coronavirus Infection

CX4945 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~days 4, 8, 11, 14, and 28
This trial's timeline: 3 weeks for screening, Varies for treatment, and days 4, 8, 11, 14, and 28 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Incidence of Treatment Emergent Adverse Events [Safety and Tolerability]
Secondary outcome measures
All-cause Mortality Status
Change in Pulse Oxygen Saturation
Changes in EQ-D5-5L
+15 more

CX4945 Trial Design

2Treatment groups
Active Control
Group I: SilmitasertibActive Control1 Intervention
Standard of care / supportive care in combination with Silmitasertib (CX-4945)
Group II: Standard of CareActive Control1 Intervention
Standard of care / supportive care

Find a Location

Who is running the clinical trial?

University of ArizonaLead Sponsor
514 Previous Clinical Trials
148,563 Total Patients Enrolled
Senhwa Biosciences, Inc.Industry Sponsor
6 Previous Clinical Trials
411 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19)
2021. "Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04668209.
~7 spots leftby Apr 2025
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