Study Summary
This trial is testing whether adding the drug eribulin to standard chemotherapy drugs may work better in treating patients with metastatic urothelial cancer.
- Stage IV Bladder Cancer
- Stage IV Urethral Cancer
- Urethral Urothelial Carcinoma
- Stage IVA Bladder Cancer
- Stage IVB Bladder Cancer
- Stage IV Ureter Cancer
- Refractory Bladder Cancer
- Stage IV Renal Pelvis and Ureter Cancer
- Metastatic Urothelial Carcinoma of the Renal Pelvis
- Refractory Renal Pelvis Urothelial Carcinoma
- Bladder Cancer
- Refractory Ureter Urothelial Carcinoma
- Refractory Urethral Urothelial Carcinoma
- Metastatic Urothelial Carcinoma of the Ureter
- Refractory Urothelial Carcinoma
- Stage IV Renal Pelvis Cancer
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 4 Secondary · Reporting Duration: 3 years
Trial Safety
Phase-Based Safety
Side Effects for
Awards & Highlights
Trial Design
3 Treatment Groups
Arm I (standard of care chemotherapy)
1 of 3
Arm II (eribulin)
1 of 3
Arm III (eribulin, gemcitabine)
1 of 3
Active Control
Experimental Treatment
465 Total Participants · 3 Treatment Groups
Primary Treatment: Eribulin Mesylate · No Placebo Group · Phase 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Are there a lot of locations where this research is taking place within the state?
"There are a hundred participating centres in this study, like the Regional Cancer Center at Indian Path Community Hospital in Kingsport, Advanced Breast Care Centre PLLC in Warren, and Genesys Hurley Cancer Institute in Flint." - Anonymous Online Contributor
For what purpose is Eribulin Mesylate most often employed?
"kaposi sarcoma can often be effectively treated with Eribulin Mesylate. However, this medication is also useful for other issues such as fallopian tubes cancer, brca1 gene, and advance directives." - Anonymous Online Contributor
Can you tell me if Eribulin Mesylate has been used in other research studies?
"At the moment, there are a total of 1431 clinical studies underway that involve Eribulin Mesylate. Of these active investigations, 420 are in Phase 3. The concentration of research is based in Shanghai but this treatment is being trialled at 70,778 locations globally." - Anonymous Online Contributor
Could you speak to the side effects that come with Eribulin Mesylate?
"Eribulin Mesylate has gone through multiple rounds of testing and there is some evidence supporting efficacy, so it received a safety score of 3." - Anonymous Online Contributor