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TAK-228 for Kidney Cancer
Study Summary
This trial is testing a drug, TAK-228, as a possible treatment for people with metastatic renal cell carcinoma.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2019 Phase 2 trial • 28 Patients • NCT02988986Trial Design
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Who is running the clinical trial?
Media Library
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Frequently Asked Questions
Has the FDA sanctioned TAK-228 for use?
"Given the lack of clinical evidence supporting efficacy, TAK-228 received a score 2 on our team's safety scale."
Are further participants being sought for this study?
"Clinicaltrials.gov indicates that this clinical trial is no longer actively recruiting; it was first posted on the 1st of August 2017 and last updated on 16th May 2022. However, there are an abundance of other medical studies currently taking applications from patients- 2582 in total."
Are there multiple sites offering this clinical research opportunity?
"The University of Colorado Cancer Center in Aurora, the Massachusetts General Hospital located in Chicago, and the Dana Farber Cancer Institute situated in La Jolla are three hubs for this clinical trial. Additionally, eight other locations have been added to the list of participating sites."
What are the expected outcomes of this research trial?
"According to the trial sponsor, Calithera Biosciences Inc., the primary objective for this study is Overall Response Rate. Data around secondary outcomes such as Median Progression Free Survival and Median Overall Survival will also be collected by means of Imaging assessments every 8 weeks (2 cycles) over a maximum 14 month period. Additionally, Radiographic progression will be tracked using Response Evaluation Criteria In Solid Tumors Criteria 1.1 which looks at an increase in target lesion size or appearance of new lesions.. Lastly, overall survival (OS) of TAK-228 in previously treated metastatic RCC patients is another key metric"
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