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Ixabepilone + Bevacizumab for Ovarian, Fallopian Tube, and Peritoneal Cancer
Study Summary
This trial is testing whether adding the drug bevacizumab to ixabepilone improves progression-free survival in patients with recurrent or persistent platinum-resistant/refractory epithelial ovarian, fallopian tube, or primary peritoneal cancer.
- Ovarian Cancer
- Peritoneal Cancer
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2015 Phase 4 trial • 45 Patients • NCT02036424Trial Design
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Who is running the clinical trial?
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- You are allergic to Cremophor® EL or polyoxyethylated castor oil.
- Group 1: Ixabepilone + Bevacizumab
- Group 2: Ixabepilone
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many participants are enrolled in this investigation?
"This trial is currently not accepting applicants. It was posted on April 3, 2017 and last updated on the 13th of April 2022. Alternatively, there are 482 clinical trials for fallopian tubes cancer and 358 studies with Bevacizumab seeking enrolment right now."
Are any participants being accepted for this research experiment currently?
"This trial is no longer open to new participants. It was initially announced on April 3rd 2017 and was last modified on April 13th 2022. However, there are currently 482 studies recruiting patients with fallopian tubes cancer and 358 trials seeking Bevacizumab users."
What are the standard uses for Bevacizumab?
"Bevacizumab is a commonly used treatment for malignant neoplasms and can help manage recurrent platinum sensitive primary peritoneal cancer, stage iv epithelial ovarian cancer following initial surgical resection, as well as locally advanced nonsquamous non-small cell lung cancer."
Has the United States Food and Drug Administration sanctioned the use of Bevacizumab?
"Taking the evidence into account, our team at Power rated Bevacizumab's safety a 2. This is due to Phase 2 trial data which suggests that it is relatively safe but there has yet to be any clinical proof of its efficacy."
Does this research protocol allow for individuals aged 18 or older to participate?
"The admission requirements for this experimental trial are ages 18 and above, up to a cap of 100 years."
Have there been previous investigations with Bevacizumab as the primary focus?
"Initially tested in 2004 at Memoral Sloan Kettering Basking Ridge, bevacizumab's clinical trials have since grown to 1077 completed studies. In the present day, a notable proportion of these 358 active trials are being conducted out of New Haven, Connecticut."
What characteristics make someone an ideal participant for this research?
"Eligible participants for this study must have a diagnosis of fallopian tubes cancer, be between the ages 18 and 100 years old, with an overall recruitment goal of 78 individuals."
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