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Device

NovoTTF-200T for Non-Small Cell Lung Cancer

Phase 3
Waitlist Available
Research Sponsored by NovoCure Ltd.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 years
Awards & highlights

Study Summary

This trial is testing a new, portable device that uses electric fields to treat stage 4 NSCLC that has progressed after other treatments.

Eligible Conditions
  • Non-Small Cell Lung Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Overall survival of patients treated with TTFields + docetaxel or immune checkpoint inhibitors vs. docetaxel or immune checkpoint inhibitors alone (superiority analysis)
Secondary outcome measures
Adverse events, severity and frequency based on Common Terminology Criteria for Adverse Events (CTCAE) V4.03
Analyses of the effects of NovoTTF-200T with each type of immune checkpoint inhibitor on overall survival and progression free survival
Squamous cell carcinoma
+7 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: NovoTTF-200TExperimental Treatment2 Interventions
Patients receive TTFields using the NovoTTF-200T device together with immune checkpoint inhibitors or docetaxel
Group II: Best Standard of CareActive Control1 Intervention
Patients receive best standard of care with immune checkpoint inhibitors or docetaxel

Find a Location

Who is running the clinical trial?

NovoCure Ltd.Lead Sponsor
57 Previous Clinical Trials
4,446 Total Patients Enrolled
NovoCure GmbHLead Sponsor
11 Previous Clinical Trials
2,463 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the most common treatments that involve Immune checkpoint inhibitors or docetaxel?

"Sarcoma, malignant neoplasms, and patients with advance directives can all be treated with either Immune checkpoint inhibitors or docetaxel."

Answered by AI

What is the total number of hospitals conducting this research project?

"With St. Joseph Heritage Healthcare in Fullerton, California, Banner MD Anderson Cancer Center at North Colorado Medical Center in Greeley, Colorado, and Saddleback Memorial Medical Center in Laguna Hills, Texas as the primary locations, this study is also running in 65 other places."

Answered by AI

Are there any slots left for volunteers in this research project?

"The clinicaltrials.gov website says that this study isn't looking for new participants at the moment. The trial was originally posted on December 1st, 2016 but the most recent update was on October 13th, 2022. There are 2414 other trials that are currently looking for participants."

Answered by AI

How many participants are being asked to join this research project?

"As of now, this study is no longer recruiting patients. Although, when it was active, the trial was posted on December 1st, 2016 and last edited on October 13th, 2022. For those still seeking studies, 2079 trials for lung cancer and 335 for Immune checkpoint inhibitors or docetaxel are still looking for patients."

Answered by AI

Are there other examples of cancer treatments that use either Immune checkpoint inhibitors or docetaxel?

"There are currently 335 active clinical trials investigating the use of immune checkpoint inhibitors or docetaxel, with 132 of those trials in Phase 3. The majority of these trials are located in Fuzhou, Fujian, but there are 22962 locations around the world conducting these trials."

Answered by AI

What immunotherapy drugs are currently available?

"Immune checkpoint inhibitors or docetaxel have a safety rating of 3, as they have undergone multiple rounds of clinical trials with positive results."

Answered by AI
Recent research and studies
~33 spots leftby Apr 2025