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Radiation Therapy

Interstitial Radiation Therapy for Breast Cancer

Phase 2

Waitlist Available

Led By Robert Mutter

Research Sponsored by Mayo Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial is testing 3 types of radiation therapy to see which is more effective in treating breast cancer.

Eligible Conditions

Breast Cancer
Ductal and Lobular Carcinoma
No change needed.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percentage difference in patients with adverse cosmesis (fair or poor cosmesis)

Secondary outcome measures

Distant recurrence

Acute Coryza

Incidence of late adverse events

+7 more

Trial Design

3Treatment groups

Experimental Treatment

Group I: Cohort III (brachytherapy APBI)Experimental Treatment4 Interventions

Patients undergo brachytherapy ABPI for 3-5 days.

Group II: Cohort II (proton APBI)Experimental Treatment4 Interventions

Patients undergo proton beam radiation therapy APBI for 3-5 days.

Group III: Cohort I (3D-CRT APBI)Experimental Treatment4 Interventions

Patients undergo 3D-CRT APBI for 3-5 days.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Proton Beam Radiation Therapy

2013

Completed Phase 2

~110

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH

13,654 Previous Clinical Trials

40,932,985 Total Patients Enrolled

940 Trials studying Breast Cancer

1,543,360 Patients Enrolled for Breast Cancer

Mayo ClinicLead Sponsor

3,205 Previous Clinical Trials

3,766,616 Total Patients Enrolled

83 Trials studying Breast Cancer

13,912 Patients Enrolled for Breast Cancer

Robert MutterPrincipal InvestigatorMayo Clinic

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What potential risks are associated with Interstitial Radiation Therapy?

"Interstitial Radiation Therapy has been assessed as a 2 on our team's 1-3 scale due to the presence of some data pertaining to its safety, although efficacy still needs further evaluation."

Answered by AI

Is there currently a recruitment process underway for this experiment?

"Data provided on clinicaltrials.gov suggests that this study is not currently looking for participants, as the experiment was first posted in June 2015 and last updated in September 2022. Notwithstanding, there are 4601 other medical studies presently recruting patients."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

3D-CRT, Proton, or Brachytherapy APBI in Treating Patients With Invasive and Non-invasive Breast Cancer

2015. "3D-CRT, Proton, or Brachytherapy APBI in Treating Patients With Invasive and Non-invasive Breast Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03391388.