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Mitomycin c for Bladder Cancer
Study Summary
This trial will study if earlier administration of mitomycin C during nephroureterectomy surgery will improve the one year bladder tumor recurrence rate in patients with urothelial carcinoma of the upper urinary tract.
- Bladder Cancer
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2023 Phase 2 trial • 29 Patients • NCT03658304Trial Design
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- You have had a bad reaction to mitomycin C in the past.
- Group 1: Mitomycin C
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the current participant capacity for this research endeavor?
"This trial is presently closed to patient recruitment. It was initially posted on December 5th 2018 and the most recent edit took place October 31st 2022. If you are searching for a different study, there exist 2515 studies actively enrolling patients with carcinoma and 40 trials recruiting participants taking Mitomycin c medications."
Is the trial accepting new applicants at this time?
"Clinicaltrials.gov reports that the given trial, first posted on December 5th 2018, is not presently accepting candidates. Nonetheless, there are currently 2555 other studies actively recruiting participants."
Can you provide details about any prior experiments regarding Mitomycin c?
"As of today, there are 40 active studies involving Mitomycin c with 10 in their terminal stage. While a handful of these clinical trials take place in Bethesda, Maryland, the drug can be studied at 2029 locations globally."
Might I be a suitable candidate for this research endeavor?
"This clinical trial is enrolling 29 individuals diagnosed with carcinoma, ranging between 18 to 99 years of age. All potential candidates must adhere to the following criteria: diagnosis of urothelial carcinoma through radiographic, pathologic or cytological findings; Eastern Cooperative Oncology Group (ECOG) performance status grade 0-2; written consent and compliance with all study related procedures; for women of childbearing potential an adequate contraception method must be employed prior to and at least three months after mitomycin C instillation in order to avoid pregnancy risk factors; males are obliged to use contraceptive methods if female partners are under consideration for conception"
Is the age limit for participation in this experiment greater than 65 years old?
"This trial only accepts applicants between 18 and 99 years old. Separately, there are 77 trials for young adults under the age of 18 and 2533 studies open to those above 65."
Has Mitomycin c been granted authorization by the FDA?
"Data from Phase 2 clinical trials suggests Mitomycin c may be relatively safe, so it was assigned a score of 2. Unfortunately, there is yet to be any data that supports its efficacy."
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