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Radiation Therapy

Radiosurgery Three Treatments for Brain Metastases (MIGRAINE Trial)

Phase 2

Waitlist Available

Led By Steven Chmura, MD

Research Sponsored by University of Chicago

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 years

Awards & highlights

MIGRAINE Trial Summary

This trial is comparing different ways to do surgery for brain cancer.

Eligible Conditions

Brain Metastases
Brain Tumor

MIGRAINE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Multi-Fraction SRS superiority compared to single fraction SRS

Secondary outcome measures

Acute CTCAE v5.0 CNS Grade 2+ and Grade 3+ toxicities

Late CTCAE v5.0 CNS Grade 2+ and Grade 3+ toxicities

Overall Survival Rate

+6 more

MIGRAINE Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Arm AExperimental Treatment1 Intervention

Group II: ARM BActive Control1 Intervention

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of ChicagoLead Sponsor

1,003 Previous Clinical Trials

819,749 Total Patients Enrolled

Steven Chmura, MDPrincipal InvestigatorUniversity of Chicago

4 Previous Clinical Trials

187 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Could you describe what safety precautions are in place for those undergoing Radiosurgery Three Treatments?

"The safety of radiosurgery three treatments was estimated to be 2, as this is a phase two trial and there exists evidence backing its security but none verifying its effectiveness."

Answered by AI

How many participants has this study recruited thus far?

"Affirmative, the details posted on clinicaltrials.gov indicate that this investigation is recruiting participants now. This research was first published to the website on June 29th 2020 and has been updated most recently on September 14th 2021. The study requires 74 subjects at one location."

Answered by AI

Are there any vacancies for people to partake in this experiment?

"Correct. The details uploaded to clinicaltrials.gov demonstrate that this medical study, which was initially announced on June 29th 2020, is presently seeking patients. 74 eligible subjects need to be found from a single facility."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Single vs Multi-fraction SRS Patients on Immunotherapy

2020. "Single vs Multi-fraction SRS Patients on Immunotherapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04427228.