Study Summary
This trial is testing a new medication to see if it is safe and effective for people with a certain eye condition.
- Age-Related Macular Degeneration (AMD)
- Age-Related Macular Degeneration
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 0 Secondary · Reporting Duration: Baseline, Month 6, Month 12
Trial Safety
Safety Progress
Side Effects for
Trial Design
2 Treatment Groups
Zimura Treatment Group
1 of 2
Sham Treatment Group
1 of 2
Experimental Treatment
Non-Treatment Group
448 Total Participants · 2 Treatment Groups
Primary Treatment: Zimura · Has Placebo Group · Phase 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| California | 28.6% |
| Florida | 28.6% |
| Ontario | 14.3% |
| Other | 28.6% |
How old are they?
| 65+ | 100.0% |
What site did they apply to?
| Retinal Consultants Medical Group, Inc. | 50.0% |
| Ochsner Medical Center | 50.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 71.4% |
| Did not meet criteria | 28.6% |
Why did patients apply to this trial?
- "More loss of vision with dirt macular degeneration. Diagnosed in 2019. Slowly progressing according to my ophthalmologist in last exam earlier in February. 2023. However, in the last 4 to 5 months I know my vision is worse. Now can’t read a newspaper, or most text without bright light and a magnifying glass. Getting very frustrating and depressed about mY AMD."
How many prior treatments have patients received?
| 0 | 100.0% |
Frequently Asked Questions
Is Zimura a new medication or has it been tested before?
"There are currently two ongoing clinical trials for Zimura, one of which is in the third and final phase. Zimura is being studied at many research centres around the world, with a particular focus in France." - Anonymous Online Contributor
Will Zimura have any harmful side effects for patients?
"Zimura's safety is estimated to be a 3, as it is a Phase 3 trial. This suggests that, not only is there some evidence of the medication's efficacy, but that there are also multiple rounds of data supporting its safety." - Anonymous Online Contributor
Do we have previous data to support the efficacy of this trial?
"Zimura is being studied in 2 ongoing trials spanning 114 cities and 20 countries. Zimura's first study was completed in 2018. IVERIC bio, Inc. sponsored the Phase 2 clinical trial which involved 120 patients. As of 2018, a total of 116 studies have been completed." - Anonymous Online Contributor
Are there any current openings for patients who might want to enroll in this trial?
"The study is not recruiting patients at this time, as indicated on clinicaltrials.gov. The trial was posted on June 22, 2020 and last updated on September 26, 2020. There are 330 other trials that are currently accepting patients." - Anonymous Online Contributor
Could you please tell us how many different hospitals are trialing this medication?
"At the moment, this trial is taking place at 100 locations, many of which are in New York (Slingerlands, Bloomfield), but also in other cities. If you decide to participate in this trial, choose a location near to reduce travel time and costs." - Anonymous Online Contributor