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Vitamin B3 Supplement

Niagen for Psoriasis

N/A

Waitlist Available

Led By Michael N Sack, M.D.

Research Sponsored by National Heart, Lung, and Blood Institute (NHLBI)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline and day 28

Awards & highlights

Study Summary

This trial is testing if the dietary supplement nicotinamide riboside can improve immune system function in people with mild to moderate psoriasis.

Eligible Conditions

Psoriasis
High Cholesterol
Cardiovascular Disease
Cardiometabolic Diseases
Obesity

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline and day 28

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline and day 28

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and day 28 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Mean Change in the TH17 Cell Cytokine IL-17 Secretion in Response to T-cell Differentiation

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Participants with mild to moderate Psoriasis receiving Nicotinamide RibosideExperimental Treatment1 Intervention

Participants with mild to moderate Psoriasis receiving Nicotinamide Riboside Chloride 500mg (2 capsules) twice daily by mouth for 28 days.

Group II: Participants with mild to moderate Psoriasis receiving PlaceboPlacebo Group1 Intervention

Participants with mild to moderate Psoriasis receiving placebo (2 capsules) twice daily by mouth for 28 days.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Niagen

2020

Completed Phase 4

~170

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Heart, Lung, and Blood Institute (NHLBI)Lead Sponsor

3,834 Previous Clinical Trials

47,310,606 Total Patients Enrolled

5 Trials studying Psoriasis

561 Patients Enrolled for Psoriasis

Michael N Sack, M.D.Principal InvestigatorNational Heart, Lung, and Blood Institute (NHLBI)

13 Previous Clinical Trials

9,209 Total Patients Enrolled

3 Trials studying Psoriasis

429 Patients Enrolled for Psoriasis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research endeavor actively enrolling participants at this time?

"Yes, the clinical trial is currently open for enrollment. According to its listing on clinicaltrials.gov, it was first posted on August 26th 2020 and most recently updated November 18th 2022."

Answered by AI

How many individuals are being accepted for inclusion in this research study?

"Affirmative. Information on clinicaltrials.gov verifies that this experiment, which was posted on August 26th 2020, is presently recruiting people to participate. Approximately 40 volunteers need to be recruited from 1 medical centre."

Answered by AI

What potential dangers have been associated with Niagen consumption?

"Due to a lack of data demonstrating Niagen's efficacy, it has been assigned as a 2 on our safety scale. Supporters can point to evidence that suggests the intervention is safe at this stage in its development."

Answered by AI

Are adolescents being considered as participants in this experiment?

"This clinical trial only accepts those aged between 18 and 80 years old. Furthermore, there are 259 trials for minors and 1206 studies dedicated to seniors respectively."

Answered by AI

Am I qualified to participate in this clinical investigation?

"This clinical trial is willing to accept 40 individuals, aged between 18-80 years old and currently suffering from psoriasis. To be eligible, the potential participants must meet all of the following criteria: gender specifications (male/female), age range (18-80) with mild to moderate active psoriasis, and willingness/ability to abide by required study protocols."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

2020. "Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04271735.