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Cannabinoid

Cannabis for Arthritis

Phase 2
Waitlist Available
Led By Elizabeth Aston, PhD
Research Sponsored by Brown University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-cannabis administration, at the termination of the cannabis administration procedure (10 minutes post-completion of cannabis administration), and 60 minutes post-completion of cannabis administration
Awards & highlights

Study Summary

This trial will study the effects of cannabis on pain, emotion, and inflammation in people with arthritis.

Eligible Conditions
  • Rheumatoid Arthritis
  • Psoriatic Arthritis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre-cannabis administration, at the termination of the cannabis administration procedure (10 minutes post-completion of cannabis administration), and 60 minutes post-completion of cannabis administration
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-cannabis administration, at the termination of the cannabis administration procedure (10 minutes post-completion of cannabis administration), and 60 minutes post-completion of cannabis administration for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Pain
Secondary outcome measures
Change in level of Inflammatory biomarkers
Change in self-reported affect

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Vaporized cannabis: medium THC/medium CBDExperimental Treatment1 Intervention
Vaporized cannabis: medium THC/medium CBD dose
Group II: Vaporized cannabis: placeboPlacebo Group1 Intervention
Vaporized cannabis: placebo dose

Find a Location

Who is running the clinical trial?

Brown UniversityLead Sponsor
456 Previous Clinical Trials
563,077 Total Patients Enrolled
Elizabeth Aston, PhDPrincipal InvestigatorBrown University
1 Previous Clinical Trials
133 Total Patients Enrolled

Media Library

Cannabis (Cannabinoid) Clinical Trial Eligibility Overview. Trial Name: NCT04269993 — Phase 2
Rheumatoid Arthritis Research Study Groups: Vaporized cannabis: placebo, Vaporized cannabis: medium THC/medium CBD
Rheumatoid Arthritis Clinical Trial 2023: Cannabis Highlights & Side Effects. Trial Name: NCT04269993 — Phase 2
Cannabis (Cannabinoid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04269993 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this a closed or open clinical trial?

"The most recent information available from clinicaltrials.gov suggests that this clinical trial is still recruiting patients. The study was first posted on 5/18/2022 and has not had any changes since then."

Answered by AI

Who does this trial require in order to be completed successfully?

"Up to 76 patients that have been diagnosed with psoriatic arthritis may be enrolled in this study, so long as they are between 18 and 65 years old. To qualify, potential participants must meet the following conditions: a current diagnosis of RA or PA where active arthritis is not being adequately controlled by standard medication (if taking prescribed steroids, NSAIDs, and/or DMARDS), stable use for at least one month prior to enrollment (this usage must be maintained throughout the study), English or Spanish fluency, negative urine toxicology screen, negative pregnancy test result, non-nursing status, effective birth control for both genders throughout the"

Answered by AI

For elderly patients, is this a good option?

"This study's age requirements state that, at a minimum, participants must be 18 years old whereas the maximum age is 65."

Answered by AI

Might there be any harmful consequences to frequently inhaling vaporized cannabis with an equal mix of THC and CBD?

"There is some supporting data for the safety of Vaporized cannabis: medium THC/medium CBD, but not enough to prove efficacy. It received a score of 2."

Answered by AI

How many patients are participating in this clinical trial?

"The information on clinicaltrials.gov supports that this trial is actively looking for participants. The posting date was 5/18/2022 and has not been updated since, meaning the search is still active. They are recruiting for a total of 76 individuals from 1 location."

Answered by AI

Has there been any research on the effects of vaporized cannabis with a moderate THC to CBD ratio?

"As of now, there are 35 ongoing studies investigating the effects of vaporized cannabis with a 3:1 ratio of THC to CBD. Most notably, these trials are being conducted in Hartford, but 51 other centres across the country are also running similar investigations."

Answered by AI
~1 spots leftby Apr 2025