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MindLight for Anxiety

Phase 2
Waitlist Available
Led By Tom Hollenstein, PhD
Research Sponsored by Queen's University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Elevated levels or clinical diagnosis of anxiety
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-tx (1st lab visit), post-tx (2nd lab visit 3 weeks later), follow-up (final lab visit 3 months later)
Awards & highlights

Study Summary

Anxiety is the most prevalent form of children's mental health problems and demand far exceeds treatment availability. Even when children do have access to care, evidence-based treatments such as cognitive-behavioural therapy have several limitations: they are largely didactic, leaving children unmotivated and disengaged; children get little practice in using the skills they are taught, creating a large gap between their knowledge and their everyday behaviour and therapy is costly, often prohibitive for the children that most need it. Therapeutic video games can address each of these gaps: they are engaging contexts through which children practice skills (rather than memorize lessons), and they cost substantially less than conventional approaches. The proposed research will test the effectiveness of MindLight, an innovative video game that targets childhood anxiety problems. MindLight incorporates several evidence-based strategies including relaxation and exposure techniques, attention bias modification methods, and neurofeedback mechanics that together produce an immersive game world through which children learn to manage and overcome anxiety symptoms. Two randomized controlled studies with 8-16 year old children are proposed to test the effectiveness of MindLight in reducing anxiety: the first is a prevention study aimed at children at risk for developing serious anxiety problems and the second is a clinical trial aimed at decreasing symptoms in anxiety-disordered children. Children randomly assigned to the intervention group will play MindLight for 5 hours over 2-3 weeks; control participants in the prevention sample will play a commercial video game with a similar theme for the same amount of time whereas control participants in the clinical sample will use an online cognitive behavioural therapy (CBT) program. Both studies will assess children's anxiety levels before the intervention, just after, and at a 3-month follow-up. Moderators (e.g., comorbidities) and mediators (e.g., attention biases) will be assessed to identify potential mechanisms of change associated with successful intervention effects.

Eligible Conditions
  • Anxiety

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre-tx (1st lab visit), post-tx (2nd lab visit 3 weeks later), follow-up (final lab visit 3 months later)
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-tx (1st lab visit), post-tx (2nd lab visit 3 weeks later), follow-up (final lab visit 3 months later) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Spence Children's Anxiety Scale following intervention

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: MindLightExperimental Treatment1 Intervention
MindLight is the video game being tested for effectiveness to reduce child anxiety
Group II: Online CBTActive Control1 Intervention
Online CBT program for children

Find a Location

Who is running the clinical trial?

Ontario Mental Health FoundationOTHER_GOV
23 Previous Clinical Trials
3,174 Total Patients Enrolled
Queen's UniversityLead Sponsor
365 Previous Clinical Trials
120,217 Total Patients Enrolled
5 Trials studying Anxiety
400 Patients Enrolled for Anxiety
Tom Hollenstein, PhDPrincipal InvestigatorQueen's University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~19 spots leftby Apr 2025