This trial will test a new treatment for a life-threatening side effect of a widely-used class of drugs.
- ACE Inhibitor Angioedema
1 Primary · 4 Secondary · Reporting Duration: Compare serum ACE activity before treatment and at 2 hours and 8 hours after treatment
2 Treatment Groups
High ACE Activity Fresh Frozen Plasma
1 of 2
1 of 2
30 Total Participants · 2 Treatment Groups
Primary Treatment: High ACE Activity Fresh Frozen Plasma · Has Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · All Participants · 6 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
- Chen, Sara X., Daniela Hermelin, and Steven J. Weintraub. 2019. “Possible Donor-dependent Differences in Efficacy of Fresh Frozen Plasma for Treatment of ACE Inhibitor–induced Angioedema”. The Journal of Allergy and Clinical Immunology: In Practice. Elsevier BV. doi:10.1016/j.jaip.2019.02.027.
- Chen SX, Hermelin D, Weintraub SJ. Possible donor-dependent differences in efficacy of fresh frozen plasma for treatment of ACE inhibitor-induced angioedema. J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):2087-2088. doi: 10.1016/j.jaip.2019.02.027. Epub 2019 Mar 2. No abstract available.
- 2020. "Treatment of Angiotensin Converting Enzyme Inhibitor-induced Angioedema". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04679311.
Frequently Asked Questions
Is the usage of High ACE Activity Fresh Frozen Plasma recognized by the FDA?
"The safety of High ACE Activity Fresh Frozen Plasma has been roughly evaluated as a 2, primarily because this is an exploratory Phase 2 trial that lacks evidence regarding efficacy but does have some background data affirming its security." - Anonymous Online Contributor
How many participants are currently enrolled in this clinical trial?
"Affirmative. According to clinicaltrials.gov, the trial commenced on December 22nd 2020 and is actively recruiting patients after its most recent edit in October 24th 2022. The study is looking for 30 individuals at one medical site." - Anonymous Online Contributor
Are there any vacancies available for prospective patients in this experiment?
"According to clinicaltrials.gov, this research study is actively recruiting participants at the time of writing. The trial was initially posted on December 22nd 2020 and has had its details most recently revised on October 24th 2022." - Anonymous Online Contributor