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Blood Transfusion

Less red blood cell transfusions for Anemia (P-OpTTICCA Trial)

Phase 3

Waitlist Available

Led By Jacques Lacroix

Research Sponsored by St. Justine's Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up one year.

Awards & highlights

P-OpTTICCA Trial Summary

This trial is testing whether it is feasible to do a larger trial on transfusion thresholds in critically-ill children with anemia.

Eligible Conditions

Anemia

P-OpTTICCA Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ one year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~one year

This trial's timeline: 3 weeks for screening, Varies for treatment, and one year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Recruitment: consent

Recruitment: enrolment

Recruitment: screening

Secondary outcome measures

Compliance

Data collection

Data entry

+5 more

P-OpTTICCA Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Restrictive arm (intervention)Experimental Treatment1 Intervention

Less red blood cell transfusions. The protocol will require that no red blood cell transfusion be given unless the hemoglobin level is below or equal at 70 g per L.

Group II: Standard care arm (comparator)Active Control1 Intervention

Clinical teams will follow their usual transfusion practices.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Hôpital Jeanne de FlandreUNKNOWN

NHS Blood and TransplantOTHER_GOV

14 Previous Clinical Trials

33,305 Total Patients Enrolled

Oxford University Hospitals NHS TrustOTHER

210 Previous Clinical Trials

1,700,755 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

For this particular research, what is the age limit of participants?

"The age parameters for this study are from 1 day old to 18 years old."

Answered by AI

Are there any vacancies in this experiment for willing individuals?

"That is correct. The listing on clinicaltrials.gov reveals that the clinical trial, which was established on June 3rd 2020, is still recruiting patients. 1 medical facility is looking for 120 individuals to participate."

Answered by AI

How can I sign up to help out with this research?

"Anemia patients, aged 1 day to 18 years old are the ideal candidates for this trial. There are two additional requirements for participants: they cannot already be enrolled in a similar study and their hemoglobin concentration must be ≤ 95 g/L."

Answered by AI

What goals does this clinical trial hope to achieve?

"The primary outcome researchers hope to achieve from this trial, which will last for one year, is a high rate of recruitment. Additionally, they hope to see high rates of compliance, minimal suspensions, and low rates of erroneous data entry."

Answered by AI

Is there a heightened risk associated with Less red blood cell transfusions?

"There is solid evidence from earlier Phase 3 trials that suggests Less red blood cell transfusions is effective and safe, with little risk to patients."

Answered by AI

How many people total are enrolled in this experiment?

"That is correct. The latest information from clinicaltrials.gov reveals that this study is still opening its doors to participants. This trial was first posted on June 3rd, 2020 and has been updated as recently as September 22nd, 2021. So far, 120 patients have been recruited from 1 site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Pilot Optimizing Transfusion Thresholds in Critically-ill Children With Anaemia

Jacques Lacroix, MD, FRCPC, Professor 2020. "Pilot Optimizing Transfusion Thresholds in Critically-ill Children With Anaemia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03871244.