Study Summary
This trial is testing a new drug for people with acromegaly who haven't been helped by other treatments. The drug is paltusotine, and it's given orally. The trial will compare the safety and effectiveness of paltusotine to a placebo.
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 4 Secondary · Reporting Duration: 24 Weeks
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
2 Treatment Groups
Paltusotine
1 of 2
Placebo
1 of 2
Experimental Treatment
Non-Treatment Group
76 Total Participants · 2 Treatment Groups
Primary Treatment: Paltusotine · Has Placebo Group · Phase 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| North Carolina | 100.0% |
How old are they?
| 18 - 65 | 100.0% |
What site did they apply to?
| Crinetics Study Site | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
Frequently Asked Questions
What precedent exists for the use of Paltusotine in medical trials?
"Paltusotine was first studied in 2019 at the Crinetics Study Site. Out of the 18,267 completed clinical trials, 3 are actively recruiting patients. A large majority of these studies are based in Los Angeles, California." - Anonymous Online Contributor
When can US patients expect Paltusotine to be available?
"Paltusotine is believed to be safe based on our scoring system which takes into account that this is a Phase 3 trial." - Anonymous Online Contributor
Are they currently looking for participants in this study?
"Yes, you're correct. The clinical trial is currently looking for patients that meet the requirements. The study was first posted on December 17th, 2021 and was last edited on October 5th, 2022. The research is enrolling a total of 76 individuals between 8 locations." - Anonymous Online Contributor
Are there many research centers conducting this trial in Canada?
"There are 11 sites total where this trial is enrolling patients. In addition to Cedars-Sinai Medical Center in Los Angeles, California and The Lundquist Institute in Portland, Oregon, Allegheny Endocrinology Associates in Torrance, Ohio are enrolling patients for this study." - Anonymous Online Contributor
Is this research fresh and new?
"Paltusotine is being trialed in 3 live trials across 35 cities and 20 countries. The first clinical trial for Paltusotine was conducted in 2019. The study, sponsored by Crinetics Pharmaceuticals Inc., involved 43 participants and completed its Phase 2 drug approval stage. Since 2019 years, 18267 trials have been completed." - Anonymous Online Contributor