← Back to Search

Liposomal bupivacaine for Pain relief

Phase 3
Waitlist Available
Led By Donald A Elmer, MD
Research Sponsored by University of Virginia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 72 hours postoperative
Awards & highlights

Study Summary

This study is evaluating whether a combination of liposomal bupivacaine and bupivacaine is more effective than plain bupivacaine for interscalene nerve block.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~72 hours postoperative
This trial's timeline: 3 weeks for screening, Varies for treatment, and 72 hours postoperative for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Opioid Consumption
Secondary outcome measures
Nerve Block Related Adverse Events
Numeric Rating Scale Reported Pain Scores
Patient Reported Satisfaction with Postoperative Pain Control Using the Numeric Rating Scale
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Liposomal BupivacaineExperimental Treatment2 Interventions
Experimental group will receive ISNB with admixed LB (10 mL) and 0.5% bupivacaine (10 mL) total of 20 mL.
Group II: Non-liposomal BupivacaineActive Control1 Intervention
Comparator group will receive ISNB with 20 mL of 0.5% non-liposomal bupivacaine
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Liposomal bupivacaine
2016
Completed Phase 4
~1970
Bupivacaine
2013
Completed Phase 4
~1530

Find a Location

Who is running the clinical trial?

University of VirginiaLead Sponsor
753 Previous Clinical Trials
1,244,954 Total Patients Enrolled
Donald A Elmer, MDPrincipal InvestigatorUniversity of Virginia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Liposomal Bupivacaine Versus Non-liposomal Bupivacaine for Total Shoulder Arthroplasty
D. Aric Elmer, MD 2021. "Liposomal Bupivacaine Versus Non-liposomal Bupivacaine for Total Shoulder Arthroplasty". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04974385.
~22 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top