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Vitamin D + fish oil for Aging

Phase 3
Waitlist Available
Led By Yanbin Dong, MD, PhD
Research Sponsored by Augusta University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
-
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 years
Awards & highlights

Study Summary

The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) was a randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or fish oil (1 gram of omega-3 fatty acids) reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses. This ancillary study is being conducted among participants in VITAL-CTSC cohort and will examine whether vitamin D or fish oil supplementation has beneficial effects on cellular aging.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in telomere length
Secondary outcome measures
Changes in Inflammation markers

Trial Design

4Treatment groups
Active Control
Placebo Group
Group I: Vitamin D + fish oilActive Control2 Interventions
Dietary supplement: Vitamin D3 (cholecalciferol), 2000 IU per day. Drug: Omega-3 fatty acids (fish oil), Omacor, 1 capsule per day. Each capsule contains 840 mg of marine omega-3 fatty acids (465 mg of eicosapentaenoic acid (EPA) and 375 mg of docosahexaenoic acid (DHA).
Group II: Vitamin D placebo + fish oilActive Control1 Intervention
Drug: Omega-3 fatty acids (fish oil), Omacor, 1 capsule per day. Dietary supplement: Vitamin D3 placebo
Group III: Vitamin D + fish oil placeboActive Control1 Intervention
Dietary supplement: Vitamin D3 (cholecalciferol), 2000 IU per day. Dietary supplement: Fish oil placebo
Group IV: Vitamin D placebo + fish oil placeboPlacebo Group2 Interventions
Dietary supplement: Vitamin D3 placebo Dietary supplement: Fish oil placebo

Find a Location

Who is running the clinical trial?

National Heart, Lung, and Blood Institute (NHLBI)NIH
3,830 Previous Clinical Trials
47,301,700 Total Patients Enrolled
6 Trials studying Aging
2,356 Patients Enrolled for Aging
Augusta UniversityLead Sponsor
210 Previous Clinical Trials
83,974 Total Patients Enrolled
1 Trials studying Aging
21,442 Patients Enrolled for Aging
Yanbin Dong, MD, PhDPrincipal InvestigatorAugusta University
3 Previous Clinical Trials
167 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effects of Vitamin D and Omega-3 Supplementation on Telomeres in VITAL
Yanbin Dong 2016. "Effects of Vitamin D and Omega-3 Supplementation on Telomeres in VITAL". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04386577.
All > Vitamin D
~122 spots leftby Apr 2025
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