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Pregnenolone 175mg for Social Isolation

Phase 2

Waitlist Available

Led By Stephanie Cacioppo, PhD

Research Sponsored by University of Chicago

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 8 weeks

Awards & highlights

Study Summary

This trial is testing the effects of the hormone pregnenolone on social threat attention, perception of others, and emotion regulation in people who feel socially isolated, using three different behavioral paradigms. The study uses electrical neuroimaging to probe the neuro-circuitry of social threat processing.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 8 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~8 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

EEG Results

Secondary outcome measures

Eye movement tracking

Trial Design

4Treatment groups

Active Control

Placebo Group

Group I: Pregnenolone 175mgActive Control1 Intervention

- Single dose of 175mg

Group II: Pregnenolone 400mgActive Control1 Intervention

- Single dose of 400mg

Group III: Matched healthy controlsActive Control1 Intervention

- No intervention

Group IV: PlaceboPlacebo Group1 Intervention

- Single dose of placebo

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of ChicagoLead Sponsor

1,004 Previous Clinical Trials

819,681 Total Patients Enrolled

Stephanie Cacioppo, PhDPrincipal InvestigatorUniversity of Chicago

1 Previous Clinical Trials

60 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Could I potentially qualify to take part in this research?

"The study team is currently looking for 96 individuals aged 21-80 who self-identify as experiencing social isolation. Other requirements for participants include: a score of 42 or higher on the UCLA Loneliness scale, right handedness, and normal or corrected vision."

Answered by AI

Are there any vacancies in this research program for new participants?

"The trial in question is not presently recruiting patients, as denoted by clinicaltrials.gov. This study was originally posted on May 1st, 2017 and received its last edit on January 15th, 2021. Although this particular trial is not looking for candidates, there are 7 other trials that are still enrolling participants."

Answered by AI

Does this research project have an age limit for participants?

"According to the prerequisites for this trial, eligible patients must be between 21 and 80 years old. There are 1 clinical trials currently looking for participants under 18 and 5 targeting a senior citizen demographic."

Answered by AI

Are there any other scientific papers that explore the effects of Pregnenolone 400mg?

"Pregnenolone 400mg is being studied in 6 different active clinical trials, none of which have reached Phase 3 yet. Most of the research regarding Pregnenolone 400mg is taking place in Dallas, Texas; however, there are 7 total locations running these trials."

Answered by AI