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Exercise for Skeletal Muscle Protein Synthesis

N/A

Waitlist Available

Led By Stuart Phillips, PhD

Research Sponsored by McMaster University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Between the ages of 18 and 30 years

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up before to 48 hours post-exercise

Awards & highlights

Study Summary

This trial will study how resistance exercise causes adaptations in the body at a molecular level.

Who is the study for?

This trial is for healthy individuals aged 18-30 who speak English and have not used investigational drugs in the last 30 days. Smokers, highly active people, or those with certain health issues like heart disease, diabetes, or uncontrolled blood pressure are excluded.Check my eligibility

What is being tested?

The study investigates how resistance exercise affects muscle proteins and their complex interactions to improve muscle mass and strength. It focuses on the changes in protein synthesis within human skeletal muscles following exercise.See study design

What are the potential side effects?

Since this trial involves standard physical exercise as an intervention without any medicinal products, side effects may include typical post-exercise symptoms such as muscle soreness or fatigue.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 30 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ before to 48 hours post-exercise

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~before to 48 hours post-exercise

This trial's timeline: 3 weeks for screening, Varies for treatment, and before to 48 hours post-exercise for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in acute muscle protein synthesis

Change in chronic muscle protein synthesis

Trial Design

1Treatment groups

Experimental Treatment

Group I: ExerciseExperimental Treatment1 Intervention

All subjects will perform both aerobic and resistance exercise

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Exercise

2016

Completed Phase 1

~760

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

McMaster UniversityLead Sponsor

884 Previous Clinical Trials

2,598,304 Total Patients Enrolled

Stuart Phillips, PhDPrincipal InvestigatorMcMaster University, Department of Kinesiology

8 Previous Clinical Trials

165 Total Patients Enrolled

Media Library

Exercise Clinical Trial Eligibility Overview. Trial Name: NCT04263714 — N/A

Skeletal Muscle Protein Synthesis Research Study Groups: Exercise

Skeletal Muscle Protein Synthesis Clinical Trial 2023: Exercise Highlights & Side Effects. Trial Name: NCT04263714 — N/A

Exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT04263714 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age limit for this experiment greater than 30 years?

"This research is accepting participants aged 18 and above, but younger than 30 years old."

Answered by AI

Are there any recruitment opportunities for this trial?

"According to clinicaltrials.gov, this specific trial is no longer recruiting volunteers; the study was initially posted on April 1st 2020 and last updated on August 22nd 2022. Despite not being able to join this particular investigation anymore, there are several other studies with open enrollment currently available."

Answered by AI

Is it possible for me to get involved in this medical experiment?

"To meet the eligibility criteria for this clinical trial, applicants must possess muscle tissue and be between 18-30 years of age. The total number of recruits required is 12 individuals."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of Exercise on the Human Skeletal Muscle Phosphoproteome

Stuart Phillips 2020. "Effect of Exercise on the Human Skeletal Muscle Phosphoproteome". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04263714.